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Titolo:
A weak signal for strong responses: Interferon-alpha/beta revisited
Autore:
Taniguchi, T; Takaoka, A;
Indirizzi:
Univ Tokyo, Grad Sch Med, Dept Immunol, Bunkyo Ku, Tokyo 1130033, Japan Univ Tokyo Tokyo Japan 1130033 Immunol, Bunkyo Ku, Tokyo 1130033, Japan Univ Tokyo, Fac Med, Bunkyo Ku, Tokyo 1130033, Japan Univ Tokyo Tokyo Japan 1130033 Fac Med, Bunkyo Ku, Tokyo 1130033, Japan
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 5, volume: 2, anno: 2001,
pagine: 378 - 386
SICI:
1471-0072(200105)2:5<378:AWSFSR>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
BINDING PROTEIN GENE; IFN-GAMMA RECEPTOR; EGF RECEPTOR; TRANSCRIPTIONAL REGULATION; TYROSINE PHOSPHORYLATION; ERYTHROPOIETIN RECEPTOR; TARGETED DISRUPTION; ANTIVIRAL DEFENSE; POSITIVE FEEDBACK; MOLECULAR-CLONING;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
94
Recensione:
Indirizzi per estratti:
Indirizzo: Taniguchi, T Univ Tokyo, Grad Sch Med, Dept Immunol, Bunkyo Ku, Hongo 7-3-1, Tokyo 1130033, Japan Univ Tokyo Hongo 7-3-1 Tokyo Japan 1130033 yo 1130033, Japan
Citazione:
T. Taniguchi e A. Takaoka, "A weak signal for strong responses: Interferon-alpha/beta revisited", NAT REV MOL, 2(5), 2001, pp. 378-386

Abstract

Biological systems have acquired adaptability and robustness against rapidenvironmental changes. A typical example is the immune system, which eradicates invading pathogens such as viruses, interferons alpha and beta, whichare produced in response to viral infection, are essential components of this system but are also produced at low levels in the absence of infection. What is the purpose of the constitutive weak interferon-alpha/beta signal?

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 09:59:55