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Titolo:
Rap1 signalling: Adhering to new models
Autore:
Bos, JL; de Rooij, J; Reedquist, KA;
Indirizzi:
Univ Utrecht, Med Ctr, Dept Physiol Chem, NL-3584 CG Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3584 CG 3584 CG Utrecht, Netherlands Univ Utrecht, Med Ctr, Ctr Biomed Genet, NL-3584 CG Utrecht, Netherlands Univ Utrecht Utrecht Netherlands NL-3584 CG 3584 CG Utrecht, Netherlands
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 5, volume: 2, anno: 2001,
pagine: 369 - 377
SICI:
1471-0072(200105)2:5<369:RSATNM>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
GTPASE-ACTIVATING-PROTEIN; NUCLEOTIDE-EXCHANGE FACTOR; NERVE GROWTH-FACTOR; REGULATED KINASES ERKS; CAMP-DEPENDENT KINASE; RAS-RELATED GENE; R-RAS; B-RAF; MAP KINASE; FUNCTIONAL INTERACTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
98
Recensione:
Indirizzi per estratti:
Indirizzo: Bos, JL Univ Utrecht, Med Ctr, Dept Physiol Chem, Univ Weg 100, NL-3584 CGUtrecht, Netherlands Univ Utrecht Univ Weg 100 Utrecht Netherlands NL-3584 CG herlands
Citazione:
J.L. Bos et al., "Rap1 signalling: Adhering to new models", NAT REV MOL, 2(5), 2001, pp. 369-377

Abstract

Ras-like GTPases are ubiquitously expressed, evolutionarily conserved molecular switches that couple extracellular signals to various cellular responses. Rap1, the closest relative of Ras, has attracted much attention because of the possibility that it regulates Ras-mediated signalling. Rap1 is activated by extracellular signals through several regulatory proteins, and itmight function in diverse processes, ranging from modulation of growth anddifferentiation to secretion, integrin-mediated cell adhesion and morphogenesis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 21:17:17