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Titolo:
Potential endocrine disrupting substances from materials in contact with drinking water
Autore:
Fawell, JK; Chipman, JK;
Indirizzi:
WRC, Marlow, Bucks, England WRC Marlow Bucks EnglandWRC, Marlow, Bucks, England Univ Birmingham, Sch Biosci, Birmingham, W Midlands, England Univ Birmingham Birmingham W Midlands England ngham, W Midlands, England
Titolo Testata:
JOURNAL OF THE CHARTERED INSTITUTION OF WATER AND ENVIRONMENTAL MANAGEMENT
fascicolo: 2, volume: 15, anno: 2001,
pagine: 92 - 96
SICI:
1360-4015(200105)15:2<92:PEDSFM>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VIVO; DI(N-BUTYL) PHTHALATE; BISPHENOL-A; RATS; TOXICITY; MICE; DI(2-ETHYLHEXYL)PHTHALATE; 4-TERT-OCTYLPHENOL; MALFORMATIONS; METABOLISM;
Keywords:
alkyl phenol; drinking water; endocrine disrupters; phthalate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Fawell, JK WRC, Marlow, Bucks, England WRC Marlow Bucks EnglandWRC, Marlow, Bucks, England
Citazione:
J.K. Fawell e J.K. Chipman, "Potential endocrine disrupting substances from materials in contact with drinking water", J CHART I W, 15(2), 2001, pp. 92-96

Abstract

At present, there is much interest in the potential effects of chemicals on the endocrine systems in animals and man. Chemicals with endocrine-disrupting potential include (a) Various phthalates, (b) compounds based on bisphenol A and F, (c) compounds based on alkyl phenols, and (d) the antioxidantbutylated hydroxyanisole. However, the potency of these chemicals in comparison with natural hormones appears to be very low. Although there is some evidence for activity in animals, high doses are usually necessary, and there is controversy and uncertainty in the interpretation of some positive findings. In addition to consideration of potential hazards, the level of exposure through leaching of these chemicals into drinking water is an important component of risk assessment. The present approval processes ensure thatsuch exposure is very low. The paper suggests a strategy for the future continued assurance of an adequate safety margin for human exposure to such substances through drinking water.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 09:42:37