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Titolo:
Aortic pulse wave velocity as a marker of cardiovascular disease in subjects over 70 years old
Autore:
Meaume, S; Rudnichi, A; Lynch, A; Bussy, C; Sebban, C; Benetos, A; Safar, ME;
Indirizzi:
Hop Broussais, Dept Internal Med, F-75674 Paris 14, France Hop Broussais Paris France 14 ept Internal Med, F-75674 Paris 14, France Charles Foix Hosp, Dept Geriatr, Ivry Sur Seine, France Charles Foix HospIvry Sur Seine France Geriatr, Ivry Sur Seine, France Charles Foix Hosp, Dept Physiol, Ivry Sur Seine, France Charles Foix HospIvry Sur Seine France Physiol, Ivry Sur Seine, France Hop Broussais, INSERM, U337, F-75674 Paris, France Hop Broussais Paris France F-75674 , INSERM, U337, F-75674 Paris, France Co Source Outsourcing Serv COVANCE, Reuil Malmaison, France Co Source Outsourcing Serv COVANCE Reuil Malmaison France aison, France
Titolo Testata:
JOURNAL OF HYPERTENSION
fascicolo: 5, volume: 19, anno: 2001,
pagine: 871 - 877
SICI:
0263-6352(200105)19:5<871:APWVAA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-PRESSURE; RISK; HYPERTENSION; DIAGNOSIS;
Keywords:
very old (over 70 years); aortic pulse wave velocity; cardiovascular mortality; drug treatment of hypertension;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Safar, ME Hop Broussais, Dept Internal Med, 96 Rue Didot, F-75674 Paris 14, France Hop Broussais 96 Rue Didot Paris France 14 674 Paris 14, France
Citazione:
S. Meaume et al., "Aortic pulse wave velocity as a marker of cardiovascular disease in subjects over 70 years old", J HYPERTENS, 19(5), 2001, pp. 871-877

Abstract

Background Aortic pulse wave velocity (PWV) is a significant and independent predictor of cardiovascular diseases (CVD) in hypertensive subjects and in patients with end-stage renal disease, but its contribution to cardiovascular risk in subjects between 70 and 100 years old has never been tested. Patients A cohort of 124 subjects (mean age: 87 +/- 7 years) was studied in two geriatric departments in a Paris suburb, Together with sphygmomanometric blood pressure measurements, aortic PWV was measured using a validated automatic device. Results Blood pressure, heart rate and body mass index, but not age, explained 48% of the PWV variability in this cohort, Furthermore, PWV was the major factor predicting the presence of CVD, The adjusted odds ratio was 17.44 (95% confidence intervals: 2.52-120.55), Antihypertensive drug therapy and low plasma albumin level had only an additive role, Blood pressure, particularly pulse pressure, had no predictive value,Conclusion In 70-100-year-old subjects, aortic PWV is a strong independentmarker of CVD, a finding that remains to be to confirmed by long-term longitudinal studies. J Hypertens 19:871-877 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:05:42