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Titolo:
Data preprocessing and partial least squares regression analysis for reagentless determination of hemoglobin concentrations using conventional and total transmission spectroscopy
Autore:
Kim, YJ; Kim, S; Kim, JW; Yoon, G;
Indirizzi:
Samsung Adv Inst Technol, Med Elect Lab, Suwon 440600, South Korea SamsungAdv Inst Technol Suwon South Korea 440600 on 440600, South Korea Samsung Biomed Res Inst, Biostat Unit, Seoul 135230, South Korea Samsung Biomed Res Inst Seoul South Korea 135230 oul 135230, South Korea Sung Kyun Kwan Univ, Sch Med, Samsung Med Ctr, Dept Clin Pathol, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 , Seoul 135710, South Korea
Titolo Testata:
JOURNAL OF BIOMEDICAL OPTICS
fascicolo: 2, volume: 6, anno: 2001,
pagine: 177 - 182
SICI:
1083-3668(200104)6:2<177:DPAPLS>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEAR-INFRARED SPECTROSCOPY; AQUEOUS-SOLUTIONS; GLUCOSE; BLOOD;
Keywords:
hemoglobin; partial least squares regression (PLSR); data preprocessing; visible-near infrared (visible-NIR) spectroscopy; reagentless; chemometrics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Engineering, Computing & Technology
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Yoon, G Samsung Adv Inst Technol, Med Elect Lab, POB 111, Suwon 440600, South Korea Samsung Adv Inst Technol POB 111 Suwon South Korea 440600 h Korea
Citazione:
Y.J. Kim et al., "Data preprocessing and partial least squares regression analysis for reagentless determination of hemoglobin concentrations using conventional and total transmission spectroscopy", J BIOMED OP, 6(2), 2001, pp. 177-182

Abstract

Visible-near infrared spectroscopy was successfully used for the determination of total hemoglobin concentration in whole blood. Absorption spectra of whole blood samples, whose hemoglobin concentrations ranged between 6.6 and 17.2 g/dL, were measured from 500 to 800 nm. Two different types of transmission were measured: conventional transmission spectroscopy which collected primarily collimated radiation transmitted through the sample, and total transmission spectroscopy which used an integrating sphere to collect allscattered light as well, Different preprocessing techniques in conjunctionwith a partial least squares regression calibration model to predict hemoglobin concentrations were applied to the above two types of transmission, Depending on different preprocessing methods, the standard error of predictions ranged from 0.37 to 2.67 g/dL, Mean centering gave the most accurate prediction in our particular data set. Preprocessing methods designed for compensation of the scattering effect produced the worst results contrary to expectations. For univariate analysis, better prediction was achieved by total transmission measurement than by conventional transmission measurement, No significant difference was observed for multivariate analysis on the other hand, Careful selection of the data preprocessing methods and of the multivariate statistical model is required for reagentless determination of hemoglobin concentration in whole blood. (C) 2001 Society oi Photo-Optical Instrumentation Engineers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/07/20 alle ore 15:18:32