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Titolo:
Early rheumatoid arthritis: can we predict its outcome?
Autore:
Williamson, AA; McColl, GJ;
Indirizzi:
Royal Melbourne Hosp, Dept Med, Ctr Rheumat Dis, Parkville, Vic 3050, Australia Royal Melbourne Hosp Parkville Vic Australia 3050 le, Vic 3050, Australia
Titolo Testata:
INTERNAL MEDICINE JOURNAL
fascicolo: 3, volume: 31, anno: 2001,
pagine: 168 - 180
SICI:
1444-0903(200104)31:3<168:ERACWP>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
EARLY INFLAMMATORY POLYARTHRITIS; HLA SHARED-EPITOPE; LONG-TERM OUTCOMES; HLA-DRB1 ALLELES; FOLLOW-UP; RADIOGRAPHIC PROGRESSION; DISEASE SEVERITY; JOINT DAMAGE; RECENT-ONSET; EXTRAARTICULAR MANIFESTATIONS;
Keywords:
early rheumatoid arthritis; genetics; outcome; prognostic factor;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
93
Recensione:
Indirizzi per estratti:
Indirizzo: Williamson, AA Royal Melbourne Hosp, Dept Med, Ctr Rheumat Dis, Parkville,Vic 3050, Australia Royal Melbourne Hosp Parkville Vic Australia 3050 ustralia
Citazione:
A.A. Williamson e G.J. McColl, "Early rheumatoid arthritis: can we predict its outcome?", INTERN M J, 31(3), 2001, pp. 168-180

Abstract

The continuing trend towards more aggressive treatment of rheumatoid arthritis (RA) has seen an increasing interest in the early phase of this chronic inflammatory disease. Optimal benefit from present and emerging therapiesis limited by our prognostic abilities during this period. The present review attempts to outline first the many methodological issues encountered instudies of early RA, and second the extent to which each major outcome measure can be explained, both by readily available clinical variables and by HLA-DR genotyping. The evidence supporting the clinical usefulness of genotyping is discussed separately Based on this information, a clinically appropriate approach to the management of early RA and the identification of patients suitable for experimental therapies is suggested.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 22:23:13