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Titolo:
Possible health impact of animal oestrogens in food
Autore:
Daxenberger, A; Ibarreta, D; Meyer, HHD;
Indirizzi:
Tech Univ Munich, Inst Physiol, D-85350 Freising, Germany Tech Univ Munich Freising Germany D-85350 iol, D-85350 Freising, Germany Joint Res Ctr EC, Inst Prospect Technol Studies, Seville, Spain Joint Res Ctr EC Seville Spain Prospect Technol Studies, Seville, Spain
Titolo Testata:
HUMAN REPRODUCTION UPDATE
fascicolo: 3, volume: 7, anno: 2001,
pagine: 340 - 355
SICI:
1355-4786(200105/06)7:3<340:PHIOAO>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESTROGEN-RECEPTOR-BETA; ANABOLIC AGENT ZERANOL; FATTY-ACID ESTERS; STEROID-HORMONES; CARCASS CHARACTERISTICS; TESTOSTERONE LEVELS; ROASTED SOYBEANS; MUSCLE TISSUES; EDIBLE TISSUES; DEFATTED MILK;
Keywords:
anabolics; food; oestradiol; oestradiol residues; public health;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
89
Recensione:
Indirizzi per estratti:
Indirizzo: Daxenberger, A Tech Univ Munich, Inst Physiol, Weihenstephaner Berg 3, D-85350 Freising, Germany Tech Univ Munich Weihenstephaner Berg 3 Freising Germany D-85350
Citazione:
A. Daxenberger et al., "Possible health impact of animal oestrogens in food", HUM REP UPD, 7(3), 2001, pp. 340-355

Abstract

Oestrogens govern reproductive functions in vertebrates, and are present in all animal tissues. The theoretical maximum daily intake (TMDI) of oestradiol-17 beta by consumption of cattle meat is calculated to be 4.3 ng, Following the use of oestradiol-containing growth-promoting agents, TMDI is increased by a factor of 4.6 to 20 ng oestradiol-17 beta ,assuming that singledosage and 'good animal husbandry' are observed. Pork and poultry probablycontain similar amounts of oestrogens as untreated cattle. The mean concentration of oestradiol-17 beta in whole milk is estimated at 6.4 pg/ml, Scarce data available on eggs report up to 200 pg/g oestradiol-17 beta, The risk evaluation of oestrogenic growth-promoting agents is limited by analytical uncertainties. Residues of oestradiol-17 alpha and the importance of oestrogen conjugates are widely unknown. The performance of mass spectrometry still needs to be improved for confirmation of oestrogen concentrations in most food. At present, the potential relevance of oestradiol acyl esters, the actual daily production rate of oestradiol in prepubertal children, and the role of oestradiol metabolites in cancer are obscure. The presence of different cytoplasmic oestrogen receptor subtypes and potential oestradiol effects in non-reproductive functions require further examination.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 02:55:50