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Titolo:
Analysis of antidepressant use through hierarchical disease analysis - Using a managed care administrative database
Autore:
Armstrong, EP;
Indirizzi:
Univ Arizona, Coll Pharm, Tucson, AZ 85721 USA Univ Arizona Tucson AZ USA85721 rizona, Coll Pharm, Tucson, AZ 85721 USA
Titolo Testata:
DISEASE MANAGEMENT & HEALTH OUTCOMES
fascicolo: 5, volume: 9, anno: 2001,
pagine: 255 - 267
SICI:
1173-8790(2001)9:5<255:AOAUTH>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRICYCLIC ANTIDEPRESSANTS; AUTOMATED DATABASES; MEDICARE PATIENTS; OUTCOMES RESEARCH; CLAIMS DATABASES; CLINICAL-DATA; DEPRESSION; QUALITY; COST; FLUOXETINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Armstrong, EP Univ Arizona, Coll Pharm, Tucson, AZ 85721 USA Univ ArizonaTucson AZ USA 85721 harm, Tucson, AZ 85721 USA
Citazione:
E.P. Armstrong, "Analysis of antidepressant use through hierarchical disease analysis - Using a managed care administrative database", DIS MANAG H, 9(5), 2001, pp. 255-267

Abstract

Objective: The purpose of this study was to evaluate the use of antidepressants through use of mutually exclusive disease indications using a managedcare database. Design and setting: A claims database from a 225 000 member managed care organisation was used for the study. A hierarchy of mutually exclusive antidepressant indications was developed: 'Depression', 'Other Approved Indication', 'Mental Health', 'Surrogate Diagnosis', 'Other Uses', 'Chronic Disease', and a residual 'Unclassified' hierarchical indication group. Main outcome measures and results: Patients in the Depression and Other Approved Indication hierarchical groups likely received the antidepressant drugs primarily for these indications and frequently received selective serotonin reuptake inhibitors (SSRIs). Use of antidepressants in the Mental Health Disorders hierarchical group may have been for a related disease. The patients in the Surrogate Diagnosis, Other Uses, Chronic Diseases, and Unclassified hierarchical groups were significantly older than those patients in the Depression group and tricyclic antidepressant (TCA) use was more frequent than the SSRIs. The patients in the Unclassified diagnosis group may represent antidepressant use that is not adequately documented or not indicated. The Surrogate Diagnosis and Chronic Diseases hierarchical groups total healthcare costs were significantly higher than those observed in patients with a Depression diagnosis. Conclusions: Use of mutually exclusive hierarchical diagnosis groups proved to be a useful strategy for assessing antidepressant drug use. SSRI use was more common in the Depression and Other Approved Indication hierarchicalgroups. Patients in the Surrogate Diagnosis. Other Uses, Chronic Diseases,and Unclassified hierarchical groups used TCAs more frequently.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 21:29:27