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Titolo:
Aspirin: past, present and future
Autore:
Elwood, PC;
Indirizzi:
Univ Wales Coll Med, Cardiff CF4 4XN, S Glam, Wales Univ Wales Coll Med Cardiff S Glam Wales CF4 4XN f CF4 4XN, S Glam, Wales
Titolo Testata:
CLINICAL MEDICINE
fascicolo: 2, volume: 1, anno: 2001,
pagine: 132 - 137
SICI:
1470-2118(200103/04)1:2<132:APPAF>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; RANDOMIZED CONTROLLED TRIAL; LOW-DOSE ASPIRIN; PLATELET-FUNCTION; PRIMARY PREVENTION; DISEASE; RISK; PHYSICIANS; THERAPY; STROKE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Elwood, PC Llandough Hosp, MRC Bldg, Penarth CF64 2XW, S Glam, Wales Llandough Hosp MRC Bldg Penarth S Glam Wales CF64 2XW am, Wales
Citazione:
P.C. Elwood, "Aspirin: past, present and future", CLIN MED, 1(2), 2001, pp. 132-137

Abstract

Many folk remedies used since prehistoric times have depended upon salicylates for their effect. One hundred years ago aspirin was formulated from salicylic and acetic acids. It was the first drug to be synthesised and its formulation is regarded as the foundation of the modern pharmaceutical industry. The benefit of low-dose aspirin as a prophylactic after a thrombotic eventwas first reported 25 years ago. Its use after coronary or cerebral thrombosis is virtually mandatory, unless there are signs of intolerance. A 'loading dose' of soluble aspirin should be given on first contact with a patient who may be suffering from myocardial infarction. Patients considered to be at increased risk of a vascular event should also be advised to carry their own aspirin and, if they experience sudden severe chest pain, to chew and swallow a 300mg tablet or a soluble preparation immediately. The current phase of the aspirin story is, however, not over, and its possible value in a variety of conditions, including dementia and certain cancers, seems likely to ensure that it will long continue to play a remarkable part in clinical practice.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 01:02:57