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Titolo:
Biochemical evaluation of oxidative stress during exercise in patients with coronary heart disease
Autore:
Andican, G; Koldas, L; Seven, A; Ayan, F; Sirmaci, N; Burcak, G;
Indirizzi:
Univ Istanbul, Cerrahpasa Med Fac, Dept Biochem, Istanbul, Turkey Univ Istanbul Istanbul Turkey a Med Fac, Dept Biochem, Istanbul, Turkey Univ Istanbul, Cerrahpasa Med Fac, Dept Cardiol, Istanbul, Turkey Univ Istanbul Istanbul Turkey a Med Fac, Dept Cardiol, Istanbul, Turkey
Titolo Testata:
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
fascicolo: 3, volume: 39, anno: 2001,
pagine: 234 - 238
SICI:
1434-6621(200103)39:3<234:BEOOSD>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
INDUCED OXIDANT STRESS; DIETARY SUPPLEMENTATION; SUPEROXIDE-DISMUTASE; LIPID-PEROXIDATION; SKELETAL-MUSCLE; FREE-RADICALS; VITAMIN-E; ANTIOXIDANT; TISSUE;
Keywords:
coronary heart disease; exercise tolerance test; oxidative stress; CuZn superoxide dismutase; glutathione peroxidase; glutathione; vitamin E; thiobarbituric acid-reactive substances (TBARS);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Andican, G Atakoy 7-8,Kisim L13 Blok,E Kapisi Da 45, Istanbul, Turkey Atakoy 7-8,Kisim L13 Blok,E Kapisi Da 45 Istanbul Turkey key
Citazione:
G. Andican et al., "Biochemical evaluation of oxidative stress during exercise in patients with coronary heart disease", CLIN CH L M, 39(3), 2001, pp. 234-238

Abstract

The impact of exercise tolerance test on oxidative stress was assessed by thiobarbituric acid reactive substances and markers of antioxidant status, namely Cu Zn superoxide dismutase, glutathione peroxidase, glutathione and vitamin E in blood samples of patients with exertional angina. The study was aimed to differentiate patients with positive exercise test (coronary heart disease patients) from patients with negative exercise test, at rest andpeak exercise with respect to the investigated variables. Significantly lower values for both glutathione peroxidase activity and glutathione level were observed in patients after exercise test (p <0.01 and p <0.05, respectively). Only the patients with positive exercise test had significantly lower values for Cu Zn superoxide dismutase, glutathione peroxidase and glutathione, and a significantly higher ratio of thiobarbituric acid reactive substances/glutathione after exercise, as compared to before (p <0.05. p <0.05. p <0.05. p <0.01, respectively). Our findings indicate that the exercise test applied to patients with exertional angina oxidatively stresses the erythrocytes to a greater extent in exercise test (+) patients than in exercise test (-) patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 11:29:47