Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Hyperhomocysteinemia and changed plasma thiol redox status in chronic obstructive pulmonary disease
Autore:
Andersson, A; Ankerst, J; Lindgren, A; Larsson, K; Hultberg, B;
Indirizzi:
Univ Lund Hosp, Dept Clin Chem, S-22185 Lund, Sweden Univ Lund Hosp LundSweden S-22185 Dept Clin Chem, S-22185 Lund, Sweden Univ Lund Hosp, Dept Internal Med, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 pt Internal Med, S-22185 Lund, Sweden Univ Lund Hosp, Dept Neurol, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 sp, Dept Neurol, S-22185 Lund, Sweden
Titolo Testata:
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
fascicolo: 3, volume: 39, anno: 2001,
pagine: 229 - 233
SICI:
1434-6621(200103)39:3<229:HACPTR>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC LUNG-DISEASE; LIPID-PEROXIDATION; TOTAL HOMOCYSTEINE; VASCULAR-DISEASE; HEALTHY-SUBJECTS; ASCORBIC-ACID; RISK FACTOR; URIC-ACID; OXIDATION; DERIVATIZATION;
Keywords:
homocysteine; lung diseases; sulphydryl compounds; oxidative stress;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Andersson, A Univ Lund Hosp, Dept Clin Chem, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 em, S-22185 Lund, Sweden
Citazione:
A. Andersson et al., "Hyperhomocysteinemia and changed plasma thiol redox status in chronic obstructive pulmonary disease", CLIN CH L M, 39(3), 2001, pp. 229-233

Abstract

Reduced and total homocysteine, cysteine, glutathione and cysteinylglycinein plasma were investigated in 19 patients with chronic obstructive pulmonary disease and in 29 healthy subjects. The purpose was to examine the influence of pro-oxidant activity caused by the lung disease on the metabolism of homocysteine and other plasma thiols. We observed a decreased concentration of reduced glutathione and a decreased ratio of reduced/total glutathione in the patients compared to the healthy individuals, which supports the hypothesis of an association between free radicals and pathogenesis in somelung diseases. We also observed an increased total plasma homocysteine. The influence of a possible extracellular pro-oxidant activity on the concentration of total plasma homocysteine is discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:56:01