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Titolo:
Hypothalamic hamartoma: the role of surgery in a series of eight patients
Autore:
Mottolese, C; Stan, H; Bret, P; Berlier, P; Lapras, C;
Indirizzi:
Hop Neurol & Neurochiurg Pierre Wertheimer, Serv Neurochirurg B, F-69003 Lyon, France Hop Neurol & Neurochiurg Pierre Wertheimer Lyon France F-69003 n, France
Titolo Testata:
CHILDS NERVOUS SYSTEM
fascicolo: 4-5, volume: 17, anno: 2001,
pagine: 229 - 236
SICI:
0256-7040(200104)17:4-5<229:HHTROS>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRUE PRECOCIOUS PUBERTY; HORMONE-RELEASING FACTOR; GELASTIC SEIZURES; SURGICAL-TREATMENT; SEXUAL PRECOCITY; TUBER CINEREUM; EPILEPSY; MR; OPERATION; CHILDREN;
Keywords:
hypothalamic hamartoma; gelastic seizures; precocious puberty; floor of third ventricle;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Mottolese, C Hop Neurol & Neurochiurg Pierre Wertheimer, Serv NeurochirurgB, 59 Blvd Pinel, F-69003 Lyon, France Hop Neurol & Neurochiurg Pierre Wertheimer 59 Blvd Pinel Lyon France F-69003
Citazione:
C. Mottolese et al., "Hypothalamic hamartoma: the role of surgery in a series of eight patients", CHILD NERV, 17(4-5), 2001, pp. 229-236

Abstract

Hypothalamic hamartoma are rare lesions. We report a new series of eight patients treated for precocious puberty (six cases) or gelastic seizures (two cases). Surgical resection was total in four cases (three pediculated andone sessile). Precocious puberty was controlled by surgical treatment in all cases. Gelastic seizures were controlled by medical treatment, but the patients did not become seizure free. We observed no mortality and no endocrinological or visual morbidity. The fact that a vascular "rete mirabilis" was observed on the surface of the lesion in our surgical material is an argument favoring a vascular mechanism in precocious puberty. Coagulation of this vascular structure can help control precocious puberty. Our series confirms that the hypothalamic hamartoma can be surgically treated when patients fail to respond to medical treatment, when the length of the treatment cannot be tolerated by the chidren and their families, and when there are uncontrolled gelastic seizures.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 22:33:04