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Titolo:
Synthesis of polyamine derivatives having non-hypotensive Ca2+-permeable AMPA receptor antagonist activity
Autore:
Yoneda, Y; Kawajiri, S; Hasegawa, A; Kito, F; Katano, S; Takano, E; Mimura, T;
Indirizzi:
Daiichi Pharmaceut Co Ltd, Med Chem Res Lab, Edogawa Ku, Tokyo 1348630, Japan Daiichi Pharmaceut Co Ltd Tokyo Japan 1348630 a Ku, Tokyo 1348630, Japan
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 10, volume: 11, anno: 2001,
pagine: 1261 - 1264
SICI:
0960-894X(20010521)11:10<1261:SOPDHN>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT HIPPOCAMPAL-NEURONS; JORO SPIDER TOXIN; ACID; PHARMACOLOGY; RESPONSES; KAINATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Yoneda, Y Daiichi Pharmaceut Co Ltd, Med Chem Res Lab, Edogawa Ku, 16-13 Kitakasai 1Chome, Tokyo 1348630, Japan Daiichi Pharmaceut Co Ltd 16-13 Kitakasai 1 Chome Tokyo Japan 1348630
Citazione:
Y. Yoneda et al., "Synthesis of polyamine derivatives having non-hypotensive Ca2+-permeable AMPA receptor antagonist activity", BIOORG MED, 11(10), 2001, pp. 1261-1264

Abstract

In order to obtain non-hypotensive and Ca2+-permeable AMPA receptor antagonists, we have synthesized a series of 1,4-bis(4-piperidinylmethyl)diaminobutanes. Compounds 13b, c, f had desirable properties. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 22:15:27