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Titolo:
Influence of hyperbranched multi-methacrylates for dental neat resins on proliferation of human gingival fibroblasts
Autore:
Wan, QC; Rumpf, D; Schricker, SR; Mariotti, A; Culbertson, BM;
Indirizzi:
Ohio State Univ, Coll Dent, Columbus, OH 43218 USA Ohio State Univ Columbus OH USA 43218 , Coll Dent, Columbus, OH 43218 USA
Titolo Testata:
BIOMACROMOLECULES
fascicolo: 1, volume: 2, anno: 2001,
pagine: 217 - 222
SICI:
1525-7797(200121)2:1<217:IOHMFD>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-VITRO; CYCLIC MONOMERS; POLYMERIZATION; COMPONENTS; CYTOTOXICITY; COMPOSITES; DIFFUSION; POLYESTER; CULTURE; CEMENTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Culbertson, BM Ohio State Univ, Coll Dent, 305 W 12th St,POB 182357, Columbus, OH 43218 USA Ohio State Univ 305 W 12th St,POB 182357 Columbus OH USA 43218
Citazione:
Q.C. Wan et al., "Influence of hyperbranched multi-methacrylates for dental neat resins on proliferation of human gingival fibroblasts", BIOMACROMOL, 2(1), 2001, pp. 217-222

Abstract

We have previously shown that hyperbranched multi-methacrylate (H-MMA)-modified dental resins have VLC activities, lower polymerization shrinkage, and improved mechanical properties, compared to the 2,2-bis [4-(2-hydroxy-3-methacryloyolxypropoxy)phenyl]propane/triethyleneglycol dimethacrylate (BisGMA/TEGDMA) neat resin. The results are due to the unique molecular structure and high molecular weight of H-MMA intermediates. The purpose of this study was to evaluate the biocompatibility of H-MMA-modified dental neat resins. The cell proliferation of three human gingival fibroblast strains or! either H-MMA, BisGMA/TEGDMA, or a polystyrene disk was examined. Following 10days of cell proliferation, there was no statistical difference in cell number between H-MMA-modified and unmodified resin disks. H-MMA-modified resins had less free monomer leaching than the unmodified resin but showed similar properties in water sorption and contact angle values. All these results suggest that the biocompatibility of H-MMA-modified dental neat resins isas good as that of commercially used BisGMA/TEGDMA resin and H-MMA has potential applications in dental composites.

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Documento generato il 11/07/20 alle ore 20:41:36