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Titolo:
Comparison of genomic DNA sequences: solved and unsolved problems
Autore:
Miller, W;
Indirizzi:
Penn State Univ, Dept Comp Sci & Engn, University Pk, PA 16802 USA Penn State Univ University Pk PA USA 16802 n, University Pk, PA 16802 USA
Titolo Testata:
BIOINFORMATICS
fascicolo: 5, volume: 17, anno: 2001,
pagine: 391 - 397
SICI:
1367-4803(200105)17:5<391:COGDSS>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONCODING SEQUENCES; REGULATORY ELEMENTS; MULTIPLE ALIGNMENTS; PAIRWISE ALIGNMENTS; SOFTWARE TOOLS; MOUSE GENOME; PROTEIN GENE; REGIONS; VISUALIZATION; CONSERVATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Miller, W Penn State Univ, Dept Comp Sci & Engn, University Pk, PA 16802 USA Penn State Univ University Pk PA USA 16802 ity Pk, PA 16802 USA
Citazione:
W. Miller, "Comparison of genomic DNA sequences: solved and unsolved problems", BIOINFORMAT, 17(5), 2001, pp. 391-397

Abstract

Motivation: The DNA sequences of entire genomes are being determined at a rapid rate. Whereas initial genome sequencing efforts were for organisms chosen to be widely spaced in the tree of life, there is a growing emphasis on projects to sequence a species that is sufficiently similar to an already-sequenced species to allow direct comparison of those two DNA sequences. This and other changes in genome sequencing strategies have created a strongneed for new methods to compare genomic sequences. Results: We sketch the current state of software for comparing genomic DNAsequences and outline research directions that we believe are likely to result in important advances in practice.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 07:01:45