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Titolo:
High lactate predicts the failure of intraaortic balloon pumping after cardiac surgery
Autore:
Davies, AR; Bellomo, R; Raman, JS; Gutteridge, GA; Buxton, BF;
Indirizzi:
Austin & Repatriat Med Ctr, Dept Intens Care, Intens Care Unit, Heidelberg, Vic 3084, Australia Austin & Repatriat Med Ctr Heidelberg Vic Australia 3084 3084, Australia Austin & Repatriat Med Ctr, Dept Cardiothorac Surg, Heidelberg, Vic 3084, Australia Austin & Repatriat Med Ctr Heidelberg Vic Australia 3084 3084, Australia
Titolo Testata:
ANNALS OF THORACIC SURGERY
fascicolo: 5, volume: 71, anno: 2001,
pagine: 1415 - 1420
SICI:
0003-4975(200105)71:5<1415:HLPTFO>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIOGENIC-SHOCK; COUNTERPULSATION; SURVIVAL; COMPLICATIONS; DETERMINANTS; SUPPORT; DEVICE; HEART;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Bellomo, R Austin & Repatriat Med Ctr, Dept Intens Care, Intens Care Unit,Austin Campus, Heidelberg, Vic 3084, Australia Austin & Repatriat Med Ctr Austin Campus Heidelberg Vic Australia 3084
Citazione:
A.R. Davies et al., "High lactate predicts the failure of intraaortic balloon pumping after cardiac surgery", ANN THORAC, 71(5), 2001, pp. 1415-1420

Abstract

Background. Despite the use of intraaortic balloon pump (IABP) support in complex cardiac surgical patients, morbidity and mortality rates are high. More advanced mechanical cardiovascular support should be considered in those patients who are highly likely to die despite IABP support. We sought toidentify early, readily available prognostic markers for patients receiving IABP support. Methods. A retrospective analysis was performed on 39 patients requiring IABP support following cardiac surgery for more than 2 years. The accuracy and predictive ability of multiple potential markers of mortality were statistically assessed. Results. Sixty-seven percent of the patients were successfully weaned fromIABP support and 46% survived to hospital discharge. Serious complicationsoccurred in 13% of patients. Serum lactate more than 10 mmol/L in the first 8 hours of IABP support predicted a 100% mortality. Base deficit more than 10 mmol/L, mean arterial pressure less than 60 mm Hg, urine output less than 30 mls/h for 2 hours, and dose of epinephrine or norepinephrine more than 10 mug/min were other highly predictive prognostic markers. Conclusions. Morbidity and mortality rates remain high despite IABP support following cardiac surgery. Mortality can be predicted by the presence of elevated serum lactate, elevated base deficit, hypotension, oliguria and large vasopressor doses, any of which should prompt appropriate considerationas to other mechanical cardiovascular support. (Ann Thorac Surg 2001;71:1415-20) (C) 2001 by The Society of Thoracic Surgeons.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 23:11:57