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Titolo:
Twenty-four-hour Tl-201 delayed scan underestimates myocardial viability in patients with acute myocardial infarction after percutaneous transluminalcoronary angioplasty
Autore:
Mochizuki, T; Murase, K; Sugawara, Y; Higashino, H; Kikuchi, T; Miyagawa, M; Ikezoe, J;
Indirizzi:
Ehime Univ, Sch Med, Dept Radiol, Shigenobu, Ehime 7910295, Japan Ehime Univ Shigenobu Ehime Japan 7910295 Shigenobu, Ehime 7910295, Japan Osaka Univ, Sch Med, Div Allied Hlth Sci, Dept Med Engn, Suita, Osaka 565,Japan Osaka Univ Suita Osaka Japan 565 i, Dept Med Engn, Suita, Osaka 565,Japan Ehime Imabari Hosp, Dept Radiol, Imabari, Ehime, Japan Ehime Imabari HospImabari Ehime Japan ept Radiol, Imabari, Ehime, Japan Ehime Natl Hosp, Dept Radiol, Matsuyama, Ehime, Japan Ehime Natl Hosp Matsuyama Ehime Japan pt Radiol, Matsuyama, Ehime, Japan
Titolo Testata:
ANNALS OF NUCLEAR MEDICINE
fascicolo: 2, volume: 15, anno: 2001,
pagine: 93 - 96
SICI:
0914-7187(200104)15:2<93:TTDSUM>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
REVERSE REDISTRIBUTION; GATED SPECT; PERFUSION;
Keywords:
thallium-201; myocardium; viability; reverse redistribution;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Mochizuki, T Ehime Univ, Sch Med, Dept Radiol, Shitsukawa, Shigenobu, Ehime 7910295, Japan Ehime Univ Shitsukawa Shigenobu Ehime Japan 7910295 95, Japan
Citazione:
T. Mochizuki et al., "Twenty-four-hour Tl-201 delayed scan underestimates myocardial viability in patients with acute myocardial infarction after percutaneous transluminalcoronary angioplasty", ANN NUCL M, 15(2), 2001, pp. 93-96

Abstract

Background: Myocardial viability in area at risk of acute myocardial infarction (AMI) after reperfusion therapy may be underestimated by the 24-hour images due to reverse redistribution (r-RD). Methods: Subjects were 37 AMI patients in whom Tc-99m pyrophosphate (PYP)/TI-201 dual-isotope SPECT was positive. The 24-hour delayed scan was performed with only a Tl window. One month later, follow up rest Tl SPECT was performed to evaluate myocardial viability. In early (at PYP/Tl-201 dual-isotope SPECT), 24-hour, and one month follow up Tl studies, Tl uptake in the area of AMI was scored into four grades: 3 as normal to 0 as severely reduced. The scores were evaluated. Results: Among the 37 AMI lesions, there were 16 r-RD, 3 RD, 16 fixed defect (FD) and 2 normal (positive PYP and normal Ti). Mean T1 scores were early; 1.4 +/- 1.1, 24-hr; 0.9 +/-0.9 and one month; 1.3 +/- 1.1. The 24-hour T1 score was lower than the early and one month Tl scores (p < 0.01). Conclusion: Reverse redistribution is frequently observed in an area at risk where PYP SPECT was positive. Nuclear medicine physicians should be aware of the existence of frequent r-RD in Tl scan to avoid the underestimationof myocardial viability in the acute phase after PTCA.

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Documento generato il 09/04/20 alle ore 19:54:16