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Titolo:
Continuous recycling: a mechanism for modulatory signal transduction
Autore:
Freeman, BC; Yamamoto, KR;
Indirizzi:
Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, San Francisco, CA94143 USA Univ Calif San Francisco San Francisco CA USA 94143 rancisco, CA94143 USA
Titolo Testata:
TRENDS IN BIOCHEMICAL SCIENCES
fascicolo: 5, volume: 26, anno: 2001,
pagine: 285 - 290
SICI:
0968-0004(200105)26:5<285:CRAMFM>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUCOCORTICOID RECEPTOR EXPRESSION; HEAT-SHOCK-PROTEIN; ESTROGEN-RECEPTOR; 26S PROTEASOME; THYMUS-CELLS; BINDING; HSP90; TRANSCRIPTION; CHAPERONES; COMPLEXES;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Freeman, BC Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, 513 Parnassus, San Francisco, CA 94143 USA Univ Calif San Francisco 513 Parnassus San Francisco CA USA 94143
Citazione:
B.C. Freeman e K.R. Yamamoto, "Continuous recycling: a mechanism for modulatory signal transduction", TRENDS BIOC, 26(5), 2001, pp. 285-290

Abstract

Modulatory signal transduction commonly requires efficient 'on demand' assembly of specific multicomponent cellular machines that convert signals to cellular actions. This article suggests that for these signaling machines to detect and respond to fluctuations in signal strength, they must be continuously disassembled in an energy-dependent process that probably involves molecular chaperones.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:20:05