Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion
Autore:
Price, LS; Collard, JG;
Indirizzi:
Netherlands Canc Inst, Div Cell Biol, NL-1066 CX Amsterdam, Netherlands Netherlands Canc Inst Amsterdam Netherlands NL-1066 CX rdam, Netherlands
Titolo Testata:
SEMINARS IN CANCER BIOLOGY
fascicolo: 2, volume: 11, anno: 2001,
pagine: 167 - 173
SICI:
1044-579X(200104)11:2<167:ROTCBR>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHOSPHOINOSITIDE 3-OH KINASE; P21-ACTIVATED KINASE; ALPHA-6-BETA-4 INTEGRIN; ACTIN CYTOSKELETON; CADHERIN FUNCTION; BINDING PROTEIN; BETA-CATENIN; LIGHT-CHAIN; MDCK CELLS; RAC;
Keywords:
Rho GTPases; cadherin; integrin; migration; invasion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
72
Recensione:
Indirizzi per estratti:
Indirizzo: Collard, JG Netherlands Canc Inst, Div Cell Biol, Plesmanlaan 121, NL-1066CX Amsterdam, Netherlands Netherlands Canc Inst Plesmanlaan 121 AmsterdamNetherlands NL-1066 CX
Citazione:
L.S. Price e J.G. Collard, "Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion", SEM CANC B, 11(2), 2001, pp. 167-173

Abstract

Rho-like GTPases regulate both cell-cell and cell-matrix adhesions and raninfluence the motile and invasive properties of tumour cells in vitro. Increased Rac signalling can promote either cell-cell adhesion or motility depending on the cell type and composition of the extracellular matrix. Ultimately, the balance of Rac and Rho activities and intracellular localization appears to be critical in determining the cellular phenotype.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 21:05:27