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Titolo:
Contextual fear-potentiated startle conditioning in humans: Replication and extension
Autore:
Ameli, R; Ip, C; Grillon, C;
Indirizzi:
Yale Univ, Sch Med, Dept Psychiat, New Haven, CT USA Yale Univ New Haven CT USA iv, Sch Med, Dept Psychiat, New Haven, CT USA
Titolo Testata:
PSYCHOPHYSIOLOGY
fascicolo: 3, volume: 38, anno: 2001,
pagine: 383 - 390
SICI:
0048-5772(200105)38:3<383:CFSCIH>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTTRAUMATIC-STRESS-DISORDER; ACOUSTIC STARTLE; GRAY LESIONS; AMYGDALA; EXPLICIT; RATS; SENSITIZATION; HIPPOCAMPUS; TERM; CUES;
Keywords:
startle; conditioning; contextual fear; fear; anxiety; humans;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Grillon, C 9000 Rockville Pike,Bldg 10,Room 3N212,MSC 1279, Bethesda, MD 20892 USA 9000 Rockville Pike,Bldg 10,Room 3N212,MSC 1279 Bethesda MD USA 20892
Citazione:
R. Ameli et al., "Contextual fear-potentiated startle conditioning in humans: Replication and extension", PSYCHOPHYSL, 38(3), 2001, pp. 383-390

Abstract

Contextual fear conditioning was examined using the startle reflex in two groups of participants over two sessions separated by 1/2 h. The conditioned stimulus (CS) was paired (paired group) or not (unpaired group) with an unpleasant shock during conditioning. The paired group showed conditioning to the CS that was well retained over the retention interval. Session 1 intertrial interval startles-a measure of contextual conditioning-were greater in the unpaired compared to the paired group. Context conditioning was retained in Session 2 and was present before the shock electrodes were attached. Self-rating of state anxiety, arousal, and pleasure indicated differential changes in mood from Session 1 to Session 2 in the two groups, with the unpaired group showing relatively greater negative affects compared to the paired group. These results indicate that unpredictable shocks lead to greater context conditioning as measured by startle and self-reports.

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Documento generato il 24/01/20 alle ore 12:19:51