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Titolo:
SLEEP BENEFIT IN PARKINSONS-DISEASE
Autore:
MERELLO M; HUGHES A; COLOSIMO C; HOFFMAN M; STARKSTEIN S; LEIGUARDA R;
Indirizzi:
RAUL CARREA INST NEUROL RES FLENI,MOVEMENT DISORDERS SECT,MONTANESES 2325 RA-1425 BUENOS AIRES DF ARGENTINA HEIDELBERG REPATRIAT HOSP,DEPT NEUROL ADELAIDE SA AUSTRALIA
Titolo Testata:
Movement disorders
fascicolo: 4, volume: 12, anno: 1997,
pagine: 506 - 508
SICI:
0885-3185(1997)12:4<506:SBIP>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC LEVODOPA THERAPY;
Keywords:
PARKINSONS DISEASE; MOTOR FLUCTUATIONS; SLEEP BENEFIT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
M. Merello et al., "SLEEP BENEFIT IN PARKINSONS-DISEASE", Movement disorders, 12(4), 1997, pp. 506-508

Abstract

Sleep benefit (SB) In Parkinson's disease (PD) is not well characterized. To determine SB frequency, as well as to characterize and correlate it with other disease variables, we evaluated prospectively a consecutive series of 312 PD patients by means of a structured questionnaire: 55% reported having SB and 35% reported that awakening was their best time of the day. Because of SB, 21% of the entire population were able to skip or delay medication. The mean duration of the phenomenon was 85.4 +/- 67 min. Patients with SB were significantly older (p < 0.0002), had disease longer (p < 0.05), and were often men (chi(2) = 3.5,df 1, p = 0.05). Patients with SB took sleep medication with similar frequency as those without SB. There were no differences in hours of sleep or sleep latency. Sleep problems such as nightmares or somnambulism, but not the number of sleep awakenings, were similar in both groups. In conclusion, SB is a frequent phenomenon, especially in men, elderly patients, and patients with longer disease duration. SB enables the morning L-dopa dose to be postponed in similar to 50% of patients.

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Documento generato il 30/11/20 alle ore 16:10:46