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Titolo:
Bacterial and viral etiology of acute otitis media in Chilean children
Autore:
Rosenblut, A; Santolaya, ME; Gonzalez, P; Corbalan, V; Avendano, LF; Martinez, MA; Hormazabal, JC;
Indirizzi:
Hosp Dr Sotero Rio, Serv Otorhinolaryngol, Santiago, Chile Hosp Dr Sotero Rio Santiago Chile erv Otorhinolaryngol, Santiago, Chile Hosp Dr Sotero Rio, Microbiol Lab, Santiago, Chile Hosp Dr Sotero Rio Santiago Chile o Rio, Microbiol Lab, Santiago, Chile Hosp Luis Calvo Mackenna, Infect Dis Unit, Santiago, Chile Hosp Luis CalvoMackenna Santiago Chile nfect Dis Unit, Santiago, Chile Fac Med, Dept Pediat, Santiago, Chile Fac Med Santiago ChileFac Med, Dept Pediat, Santiago, Chile Univ Chile, Fac Med, Dept Pediat, Santiago 7, Chile Univ Chile Santiago Chile 7 ile, Fac Med, Dept Pediat, Santiago 7, Chile Univ Chile, Fac Med, Inst Ciencias Biomed, Virol Program, Santiago 7, Chile Univ Chile Santiago Chile 7 ias Biomed, Virol Program, Santiago 7, Chile Univ Chile, Fac Med, Inst Ciencias Biomed, Microbiol Program, Santiago 7, Chile Univ Chile Santiago Chile 7 Biomed, Microbiol Program, Santiago 7, Chile Inst Salud Publ Chile, Dept Clin Microbiol, Santiago, Chile Inst Salud Publ Chile Santiago Chile pt Clin Microbiol, Santiago, Chile
Titolo Testata:
PEDIATRIC INFECTIOUS DISEASE JOURNAL
fascicolo: 5, volume: 20, anno: 2001,
pagine: 501 - 507
SICI:
0891-3668(200105)20:5<501:BAVEOA>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESISTANT STREPTOCOCCUS-PNEUMONIAE; RESPIRATORY SYNCYTIAL VIRUS; MIDDLE-EAR; CONJUGATE VACCINE; TRACT INFECTION; SUSCEPTIBILITY; SURVEILLANCE; PNEUMOCOCCUS; MANAGEMENT; DIAGNOSIS;
Keywords:
acute otitis media;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Rosenblut, A Los Huasos 1948,Las Condes, Santiago, Chile Los Huasos 1948,Las Condes Santiago Chile Santiago, Chile
Citazione:
A. Rosenblut et al., "Bacterial and viral etiology of acute otitis media in Chilean children", PEDIAT INF, 20(5), 2001, pp. 501-507

Abstract

Background. Acute otitis media (AOM) is a main cause for antimicrobial prescription in Latin America. Pathogen diversity in different geographic regions underscores the need for updated knowledge on AOM microbiology. Aim. To prospectively determine the role of bacteria and viruses in Chilean children with AOM,Methods. Between July, 1998, and June, 1999, children >3 months with a presumptive diagnosis of AOM were referred to the study ear, nose and throat physician. Middle ear fluid and nasopharyngeal aspirates were obtained from children with confirmed AOM and processed for common bacteria, Mycoplasma pneumoniae, Chlamydia pneumoniae and viruses. Antimicrobial susceptibility patterns and serotypes of Streptococcus pneumoniae strains were determined. Results. An ear, nose and throat physician confirmed diagnoses for 222 (42%) of 529 children referred with diagnosis of AOM, and 170 children met eligibility criteria for the study. One or more pathogens were detected in 140of 170 (82%) children. Predominant bacteria were S, pneumoniae (37%), Haemophilus influenzae (24%) and Streptococcus pyogenes (13%). IM, catarrhalis was detected in 2 children, C, pneumoniae was found in 1 and M, pneumoniae was not detected. Viruses were detected in 22 children (13%) from nasopharyngeal aspirates, and in 6 of them the same virus was detected in middle earfluid. Penicillin-resistant (intermediate and high) S, pneumoniae represented 40% of isolates and 10% of H, influenzae were beta-lactamase producers. All 10 penicillin-resistant S. pneumoniae strains were resistant to cefuroxime, Eighteen S, pneumoniae serotypes were detected and 19F was associatedwith high level penicillin resistance. Conclusion. This study can impact local management of AOM, and it should encourage continuous surveillance of AOM microbiology in Chile and other developing countries.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:31:03