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Titolo:
Antioxidant capacity in severely burned patients
Autore:
Farriol, M; Fuentes, F; Venereo, Y; Solano, I; Orta, X; Segovia, T;
Indirizzi:
Hosp Gen Valle Hebron, Ctr Invest Bioquim & Biol Mol, Barcelona 08035, Spain Hosp Gen Valle Hebron Barcelona Spain 08035 Mol, Barcelona 08035, Spain Hosp Gen Valle Hebron, Ctr Atencio Primaria Manso, Barcelona 08035, Spain Hosp Gen Valle Hebron Barcelona Spain 08035 anso, Barcelona 08035, Spain Hosp Gen Valle Hebron, Serv Cremats, Barcelona 08035, Spain Hosp Gen ValleHebron Barcelona Spain 08035 mats, Barcelona 08035, Spain
Titolo Testata:
PATHOLOGIE BIOLOGIE
fascicolo: 3, volume: 49, anno: 2001,
pagine: 227 - 231
SICI:
0369-8114(200104)49:3<227:ACISBP>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
INJURY;
Keywords:
antioxidant capacity; burns; reference values;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Farriol, M Hosp Gen Valle Hebron, Ctr Invest Bioquim & Biol Mol, Passieg Vall Hebron 119-129, Barcelona 08035, Spain Hosp Gen Valle Hebron Passieg Vall Hebron 119-129 Barcelona Spain 08035
Citazione:
M. Farriol et al., "Antioxidant capacity in severely burned patients", PATH BIOL, 49(3), 2001, pp. 227-231

Abstract

Total antioxidant capacity (TAC) was measured after severe burns (non-electric with one exception) in two groups of patients: group A, 24 subjects (19 men and five women) 20-67 years old and group B, eight subjects (six men and two women) 20-54 years old, admitted to the Major Burns Unit of hospital general Vall d'Hebron over a period of nine months. Albumin, uric acid and antioxidant capacity analyses were carried out within 24 hours after injury in both groups, and additionally at 1, 7, 15 and 21 days in group B. Total antioxidant capacity was measured by inhibition of blue-green colour of the ABTS(+) cation (600 nm) and compared with reference values obtained in healthy, sex and age-matched volunteers (n = 50). Results showed statistically increased mean antioxidant capacity values at 24 hours (Group A: 1.36 +/- 0.22 mmol/L; Group B: 1.66 +/- 0.39) as compared with reference values (rage, 1.0 to 1.44 mmol/L), representing 42% of patients in group A and 50% in group B (overall mean 46%), with no correlation with severity of the burn. The longitudinal study (Group B) showed no correlation between total antioxidant capacity values and time (r = -0.171; ns). A statistically significant correlation was found between albumin and time (r = 0.438; p < 0.05), indicating a clear tendency toward normalisation of plasma albumin values during healing. There was no correlation among total antioxidant capacity, percentage of burned surface and clinical evolution, suggesting a poor sensitivity of the method for the study of this pathology. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

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Documento generato il 23/11/20 alle ore 21:30:59