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Titolo:
Prolonged QRS duration increases QT dispersion but does not relate to arrhythmias in survivors of acute myocardial infarction
Autore:
Kirchhof, P; Eckardt, L; Arslan, O; Reinhardt, L; Monnig, G; Fetsch, T; Breithardt, G; Borggrefe, M; Haverkamp, W;
Indirizzi:
Univ Kliniken Munster, Med Klin & Poliklin, Dept Cardiol & Angiol, D-48129Munster, Germany Univ Kliniken Munster Munster Germany D-48129 l, D-48129Munster, Germany Univ Munster, Inst Arteriosclerosis Res, D-4400 Munster, Germany Univ Munster Munster Germany D-4400 lerosis Res, D-4400 Munster, Germany
Titolo Testata:
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
fascicolo: 5, volume: 24, anno: 2001,
pagine: 789 - 795
SICI:
0147-8389(200105)24:5<789:PQDIQD>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
REENTRANT VENTRICULAR ARRHYTHMIAS; SIGNAL-AVERAGED ELECTROCARDIOGRAM; HEART-RATE-VARIABILITY; TORSADE-DE-POINTES; PROGNOSTIC-SIGNIFICANCE; LATE POTENTIALS; EJECTION FRACTION; RISK; TACHYCARDIA; MORTALITY;
Keywords:
dispersion of repolarization; late potentials; signal-averaged EGG; myocardial infarction; risk stratification; ventricular arrhythmias; sudden cardiac death;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Kirchhof, P Univ Kliniken Munster, Med Klin & Poliklin, Dept Cardiol & Angiol, D-48129Munster, Germany Univ Kliniken Munster Munster Germany D-48129 nster, Germany
Citazione:
P. Kirchhof et al., "Prolonged QRS duration increases QT dispersion but does not relate to arrhythmias in survivors of acute myocardial infarction", PACE, 24(5), 2001, pp. 789-795

Abstract

QT dispersion has been suggested and disputed as a risk marker for ventricular arrhythmias after myocardial infarction. Delayed ventricular activation after myocardial infarction may affect arrhythmic risk and QT intervals. This study determined if delayed activation as assessed by (1) QRS durationin the 12-lead ECG and by (2) late potentials in the signal-averaged ECG affects QT dispersion and its ability to assess arrhythmic risk after myocardial infarction. QT duration, JT duration, QT dispersion, and JT dispersionwere compared to QRS duration in the 12-lead ECG and to late potentials inthe signal-averaged ECG recorded in 724 patients 2-3 weeks after myocardial infarction. Prolonged QRS duration (> 110 ms) and high QRS dispersion increased QT and JT dispersion by 12%-15% (P < 0.05). Presence of late potentials, in contrast, did not change QT dispersion. Only the presence of late potentials (n = 113) was related to arrhythmic events during 6-month follow-up. QT dispersion, JT dispersion, QRS duration, and QRS dispersion were equal in patients with (n = 29) and without arrhythmic events (QT disp 80 +/- 7 vs 78 +/- 1 ms, JT disp 80 +/- 6 vs 79 +/- 2 ms, mean +/- SEM P > 0.2). In conclusion, prolonged QRS duration increases QT dispersion irrespective of arrhythmic events in survivors of myocardial infarction. Presence of latepotentials, in contrast, relates to arrhythmic events but does not affect QT dispersion. Therefore, QT dispersion may not be an adequate parameter toassess arrhythmic risk in survivors of myocardial infarction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 05:10:05