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Titolo:
Research and treatment approaches to depression
Autore:
Wong, ML; Licinio, J;
Indirizzi:
Univ Calif Los Angeles, Sch Med,Clin Pharmacol Program, Gonda Neurosci & Genet Res Ctr, Lab Pharmacogen,Neuropsychiat Inst,Brain Res Inst, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA
Titolo Testata:
NATURE REVIEWS NEUROSCIENCE
fascicolo: 5, volume: 2, anno: 2001,
pagine: 343 - 351
SICI:
1471-0048(200105)2:5<343:RATATD>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
BORNA-DISEASE VIRUS; CORTICOTROPIN-RELEASING HORMONE; SEROTONIN TRANSPORTER GENE; PITUITARY-ADRENAL AXIS; ANTIDEPRESSANT-INDUCED REMISSION; IL-1 RECEPTOR ANTAGONIST; CENTRAL-NERVOUS-SYSTEM; MAJOR DEPRESSION; PSYCHIATRIC-DISORDERS; THERAPEUTIC IMPLICATIONS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
101
Recensione:
Indirizzi per estratti:
Indirizzo: Wong, ML Univ Calif Los Angeles, Sch Med,Clin Pharmacol Program, Gonda Neurosci & Genet Res Ctr, Lab Pharmacogen,Neuropsychiat Inst,Brain Res Inst, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 es, CA 90095 USA
Citazione:
M.L. Wong e J. Licinio, "Research and treatment approaches to depression", NAT REV NEU, 2(5), 2001, pp. 343-351

Abstract

Depression is a major cause of disability worldwide, but we know little about the underlying fundamental biology. Research its hindered by the difficulties of modelling a disorder of higher cognitive functions in animals. Depression can be understood as the interaction of genetic susceptibility andenvironmental factors; however, current classifications are purely descriptive. The complexity of this field is best approached by rigorous explorations of known candidate systems in conjunction with the use of genomic: tools to discover new targets for antidepressants and to predict therapeutic outcomes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/20 alle ore 20:18:39