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Titolo:
Schizophrenia
Autore:
Goff, DC; Heckers, S; Freudenreich, O;
Indirizzi:
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Schizophrenia Program, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 izophrenia Program, Boston, MA 02115 USA
Titolo Testata:
MEDICAL CLINICS OF NORTH AMERICA
fascicolo: 3, volume: 85, anno: 2001,
pagine: 663 -
SICI:
0025-7125(200105)85:3<663:S>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAGNETIC-RESONANCE SPECTROSCOPY; MEDIAL TEMPORAL-LOBE; CEREBRAL BLOOD-FLOW; POSITRON-EMISSION TOMOGRAPHY; HIPPOCAMPAL PYRAMIDAL CELL; BASAL GANGLIA; TARDIVE-DYSKINESIA; PREFRONTAL CORTEX; NEGATIVE SYMPTOMS; NEURONAL DENSITY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
228
Recensione:
Indirizzi per estratti:
Indirizzo: Goff, DC 25 Staniford St, Boston, MA 02114 USA 25 Staniford St Boston MA USA 02114 ord St, Boston, MA 02114 USA
Citazione:
D.C. Goff et al., "Schizophrenia", MED CLIN NA, 85(3), 2001, pp. 663

Abstract

Schizophrenia is a chronic psychiatric illness characterized by psychosis,"negative symptoms," apathy and withdrawal, subtle cognitive deficits, a lack of insight, and deterioration of functioning. Although the etiology hasnot been fully established, schizophrenia clearly has a genetic component. Abnormalities of cellular distribution have been observed in postmortem brain, and abnormal patterns of brain activation have been observed in neuroimaging studies. Antipsychotic medication controls most symptoms, although patients often remain disabled by the illness and at risk for relapse. Because the newer antipsychotics seem to be more effective for cognitive deficits and for apathy their use has facilitated advances in psychosocial rehabilitation of individuals with this illness.

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Documento generato il 22/01/20 alle ore 12:50:06