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Titolo:
Secondary myeloid/natural killer cell acute leukemia following T-cell lymphoma
Autore:
Lee, JJ; Kim, HJ; Chung, IJ; Park, MR; Ryang, DW; Choi, C;
Indirizzi:
Chonnam Natl Univ, Sch Med, Dept Internal Med, Dong Ku, Kwangju 501757, South Korea Chonnam Natl Univ Kwangju South Korea 501757 Kwangju 501757, South Korea
Titolo Testata:
LEUKEMIA & LYMPHOMA
fascicolo: 3-4, volume: 41, anno: 2001,
pagine: 457 - 460
SICI:
1042-8194(200104)41:3-4<457:SMKCAL>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRECURSOR ACUTE-LEUKEMIA; PREVIOUSLY UNRECOGNIZED FORM; ACUTE MYELOID-LEUKEMIA; NON-HODGKINS-LYMPHOMA; MALIGNANCIES;
Keywords:
secondary myeloid/NK cell acute leukemia; T-cell lymphoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, HJ Chonnam Natl Univ, Sch Med, Dept Internal Med, Dong Ku, 8 Hakdong,Kwangju501757, South Korea Chonnam Natl Univ 8 Hakdong Kwangju South Korea 501757 outh Korea
Citazione:
J.J. Lee et al., "Secondary myeloid/natural killer cell acute leukemia following T-cell lymphoma", LEUK LYMPH, 41(3-4), 2001, pp. 457-460

Abstract

A 56-year-old woman was treated with combination chemotherapy and radiation therapy for peripheral T-cell lymphoma. Following complete remission for a period of 6 months, she returned again with marked leukocytosis. Leukemiccells were characterized by scanty cytoplasm with fine azurophilic granules, and were highly positive for myeloperoxidase and sudan black-B. Immunophenotypic analysis revealed that blast cells were positive for myeloid antigens (CD13, CD33), and natural killer (NK) cell antigen (CD56), but negativefor T-cell antigens (CD2, CD5, CD7), B-cell antigens (CD19, CD20), CD34, and HLA-DR. The case was diagnosed as secondary myeloid/NK cell acute leukemia following non-Hodgkin's lymphoma, Despite aggressive chemotherapy against leukemia, she died of multiorgan failure 7 months following onset of Leukemia. We present. to the best of our knowledge. the first published report of what seems to be a secondary myeloid/NK cell acute leukemia following T-cell lymphoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 00:28:18