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Titolo:
C-13 breath tests: Visions and realities
Autore:
Klein, PD;
Indirizzi:
Meretek Diagnost Inc, Res & Dev, Houston, TX 77030 USA Meretek Diagnost Inc Houston TX USA 77030 es & Dev, Houston, TX 77030 USA Baylor Coll Med, Dept Pediat, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 , Dept Pediat, Houston, TX 77030 USA Baylor Coll Med, Dept Med, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 Med, Dept Med, Houston, TX 77030 USA
Titolo Testata:
JOURNAL OF NUTRITION
fascicolo: 5, volume: 131, anno: 2001,
pagine: 1637S - 1642S
SICI:
0022-3166(200105)131:5<1637S:CBTVAR>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
HELICOBACTER-PYLORI INFECTION; GASTRIC-EMPTYING RATE; LIVER-FUNCTION; NONINVASIVE ASSESSMENT; ENZYME-INDUCTION; N-DEMETHYLATION; HUMAN-BEINGS; UREA; ACID; CAFFEINE;
Keywords:
H. pylori; carbon-13; (CO2)-C-13; diagnostic test; noninvasive;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
95
Recensione:
Indirizzi per estratti:
Indirizzo: Klein, PD Meretek Diagnost Inc, Res & Dev, 618 Grassmere Pk Dr,Suite 20, Houston, TX77030 USA Meretek Diagnost Inc 618 Grassmere Pk Dr,Suite 20 Houston TX USA 77030
Citazione:
P.D. Klein, "C-13 breath tests: Visions and realities", J NUTR, 131(5), 2001, pp. 1637S-1642S

Abstract

Breath tests have been used in research laboratories for over 25 y. Originally, the tests were based on the use of C-14, rather than on the nonradioactive isotope,C-13. When C-13 became widely available at a reasonable cost,research groups in the United States and Europe developed methodologies tomeasure C-13 abundance in samples of CO2. The tests used a variety of substrates and measured pancreatic function, fat absorption, bacterial overgrowth and P-450 mixed-function oxidase, Thus far, the only test to be approvedby the Food and Drug Administration is the C-13-urea breath test. This manuscript describes the process by which approval is gained, and indicates the steps necessary for other tests to receive Food and Drug Administration approval.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 11:47:26