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Titolo:
Structure and neurotrophic activity of seco-prezizaane-type sesquiterpenesfrom Illicium merrillianum
Autore:
Huang, JM; Yokoyama, R; Yang, CS; Fukuyama, Y;
Indirizzi:
Tokushima Bunri Univ, Fac Pharmaceut Sci, Inst Pharmacognosy, Yamashiro, Tokushima 7708514, Japan Tokushima Bunri Univ Yamashiro Tokushima Japan 7708514 ima 7708514, Japan Beijing Univ Chin Med, Fac Pharmaceut Sci, Beijing 100029, Peoples R ChinaBeijing Univ Chin Med Beijing Peoples R China 100029 29, Peoples R China
Titolo Testata:
JOURNAL OF NATURAL PRODUCTS
fascicolo: 4, volume: 64, anno: 2001,
pagine: 428 - 431
SICI:
0163-3864(200104)64:4<428:SANAOS>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERICARPS; LACTONES; MAJUS; DERIVATIVES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Fukuyama, Y Tokushima Bunri Univ, Fac Pharmaceut Sci, Inst Pharmacognosy, Yamashiro, Tokushima 7708514, Japan Tokushima Bunri Univ Yamashiro Tokushima Japan 7708514 Japan
Citazione:
J.M. Huang et al., "Structure and neurotrophic activity of seco-prezizaane-type sesquiterpenesfrom Illicium merrillianum", J NAT PROD, 64(4), 2001, pp. 428-431

Abstract

An extract of the pericarps of Illicium merrillianum has yielded four new sesquiterpenes: 3 alpha -hydroxycycloparvifloralone (1), 1,2-dehydrocycloparvifloralone (2), (11) 7,14-ortholactone-3 alpha -hydroxyfloridanolide (3),and 11-O-debenzoyltashironin (4) along with cycloparvifloralone (5), merrillianone (6), and tashironin (7). The structures of 1-4 were determined on the basis of spectroscopic analyses. 11-O-Debenzoyltashironin (4) showed neurotrophic activity in primary culture of rat cortical neurons at 0.1-10 muM. However, cycloparvifloralone-type sesquiterpenes (1, 2, 5, and 6) and tashironin (7) had no neurotrophic activity at these concentrations.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/08/20 alle ore 15:41:02