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Titolo:
Circadian rhythm and postural change in natriuresis in non-dipper type of essential hypertension
Autore:
Uzu, T; Takeji, M; Yamauchi, A; Kimura, G;
Indirizzi:
Osaka Rosai Hosp, Div Nephrol, Sakai, Osaka 5918025, Japan Osaka Rosai Hosp Sakai Osaka Japan 5918025 l, Sakai, Osaka 5918025, Japan
Titolo Testata:
JOURNAL OF HUMAN HYPERTENSION
fascicolo: 5, volume: 15, anno: 2001,
pagine: 323 - 327
SICI:
0950-9240(200105)15:5<323:CRAPCI>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-PRESSURE; ORTHOSTATIC HYPOTENSION; SODIUM SENSITIVITY; NONDIPPER;
Keywords:
blood pressure; circadian rhythm; natriuresis; posture; kidney;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Uzu, T Osaka Rosai Hosp, Div Nephrol, 1179-3 Nagasone Cho, Sakai, Osaka 5918025, Japan Osaka Rosai Hosp 1179-3 Nagasone Cho Sakai Osaka Japan 5918025apan
Citazione:
T. Uzu et al., "Circadian rhythm and postural change in natriuresis in non-dipper type of essential hypertension", J HUM HYPER, 15(5), 2001, pp. 323-327

Abstract

Recently we found that, in non-dipper type of essential hypertensive patients who showed the lack of nocturnal fall in blood pressure, circadian rhythm of urinary sodium excretion rate was disturbed. In the present study we examined whether postural change in natriuresis is also disturbed in non-dippers, Sixteen inpatients with essential hypertension were maintained on a relatively high sodium diet containing 10 to 12 g of NaCl per day for 8 days, On the 7th day of the study period, 24-h ambulatory blood pressures weremeasured, and 5-7th days urinary samples were collected for both daytime and night-time. On the last day of the study period, patients stood for 2 h and then lay down for 2 h, Urinary volume and excretion rates of creatinineand sodium were measured every hour in both positions. Night-time urinary sodium excretion rate was significantly higher in non-dippers (n = 9) than that in dippers (n = 7), Night/day ratio of mean arterial pressure had a positive relationship with night/day ratio of urinary sodium excretion rate. In non-dippers, but not in dippers, the mean value of U,,V during upright position was significantly lower than that during supine position. There wasa significantly negative relationship between upright/supine ratio of U,,Vand night/day ratio of MAP or night/day ratio of U,,V, In patients with non-dipper type of essential hypertension, both natriuresis patterns, circadian rhythm and postural change, were disturbed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 11:58:29