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Titolo:
Can estrogen influence the response to noxious stimuli?
Autore:
Tsen, LC; Natale, M; Datta, S; Eappen, S;
Indirizzi:
Harvard Univ, Brigham & Womens Hosp, Dept ANesthesia Perioperat & Pain Med, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 ioperat & Pain Med, Boston, MA 02115 USA
Titolo Testata:
JOURNAL OF CLINICAL ANESTHESIA
fascicolo: 2, volume: 13, anno: 2001,
pagine: 118 - 121
SICI:
0952-8180(200103)13:2<118:CEITRT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESSURE PAIN THRESHOLDS; INDUCED ANTINOCICEPTION; BETA-ENDORPHIN; FEMALE RATS; RECEPTOR; BRAIN; COLD; REPRODUCIBILITY; HYPERALGESIA; PROGESTERONE;
Keywords:
estrogen; in vitro fertilization; pressure; nociception : cold thermal;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Tsen, LC Harvard Univ, Brigham & Womens Hosp, Dept ANesthesia Perioperat &Pain Med, CWN-I 1,75 Francis St, Boston, MA 02115 USA Harvard Univ CWN-I 1,75 Francis St Boston MA USA 02115 02115 USA
Citazione:
L.C. Tsen et al., "Can estrogen influence the response to noxious stimuli?", J CLIN ANES, 13(2), 2001, pp. 118-121

Abstract

Study Objective: To evaluate estrogen-induced alternations in noxious stimuli response. Design: Randomized, prospective, double-blind study. Setting: Tertiary-care academic medical center. Patients: 40 ASA physical status I and II women at the beginning and conclusion of an in vitro fertilization stimulation cycle. Interventions: Stimuli were applied to the fingers of the dominant hand via a Basile Analgesy-Meter, which applied increasing pressure (g/cm(2)) in acontinuous fashion, and ice water immersion. Measurements: Serum hormonal concentrations and responses to noxious (pressure and cold thermal) stimuli were studied. Main Results: Estrogen and progesterone concentrations changed from 377 +/- 323.42 pg/mL to 2078.05 +/- 1175.92 pg/mL (p < 0.001) and 1.20 +/- 0.56 to 1.03 +/- 0.35 ng/mL (p = NS), respectively. Although no significant difference was noted in the response to pressure (16.92 +/- 4.41 to 17.85 +/- 4.95 g.cm(2)), a significant reduction in the tolerance to ice water immersion (34.18 +/- 28.29 to 24.05 +/- 23.02 s) was observed. Conclusions: High estrogen concentrations are associated with significantly lower tolerance to cold. but not pressure stimuli. (C) 2001 by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 14:10:54