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Titolo:
Adaptation of distortion product otoacoustic emission in humans
Autore:
Kim, DO; Dorn, PA; Neely, ST; Gorga, MP;
Indirizzi:
Univ Connecticut, Ctr Hlth, Dept Neurosci,Div Otolaryngol, Dept Surg, Farmington, CT 06030 USA Univ Connecticut Farmington CT USA 06030 t Surg, Farmington, CT 06030 USA Boys Town Natl Res Hosp, Omaha, NE 68131 USA Boys Town Natl Res Hosp Omaha NE USA 68131 Res Hosp, Omaha, NE 68131 USA
Titolo Testata:
JARO
fascicolo: 1, volume: 2, anno: 2001,
pagine: 31 - 40
SICI:
1525-3961(200103)2:1<31:AODPOE>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTRALATERAL SOUND; COCHLEAR MECHANICS; ACTION-POTENTIALS; FINE-STRUCTURE; HAIR-CELLS; STIMULATION; SUPPRESSION; RESPONSES; 2F1-F2; DPOAE;
Keywords:
olivocochlear; efferent; reflex; feedback; cochlear mechanics; auditory; hearing;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, DO Univ Connecticut, Ctr Hlth, Dept Neurosci,Div Otolaryngol, Dept Surg, Farmington, CT 06030 USA Univ Connecticut Farmington CT USA 06030 Farmington, CT 06030 USA
Citazione:
D.O. Kim et al., "Adaptation of distortion product otoacoustic emission in humans", JARO, 2(1), 2001, pp. 31-40

Abstract

Previous studies of animals observed a phenomenon of adaptation of distortion product otoacoustic emission (DPOAE) and found that the phenomenon was mediated to a large extent by the medial olivocochlear (MOC) reflex. The present study investigated DPOAE adaptation in humans. The following stimuli were used: f(2)/f(1) = 1.2; f(2) = 2, 4, or 5.65 kHz; L-2 = 50-65 dB SPL re20 mu Pa rms, L-1 - L-2 = 0-15 dB, where L-1 and L-2 represent levels of the f(1) and f(2) tones, respectively; duration of two-tone burst = 5.5 s; interburst gap 20 or 30 s; number of repetitions = 40 or 64, We analyzed the(2)f(1) - f(2) DPOAE as a function of time using a method of heterodyne envelope detection. The subjects were 20 humans aged from 15 to 54 years (median = 21 years) with normal hearing. We observed that (1) humans exhibited DPOAE adaptation phenomenon; (2) the time course of DPOAE level was characterized by a 2-exponential function; (3) distributions of the fast and slow time constants were well, separated with their median values being 69 ms and 1.51 s, respectively; (4) distributions of the magnitudes of the fast andslow adaptation components were largely overlapped with their median values being 0.65 and 0.40 dB, respectively; and (5) the combined magnitude of the adaptation ranged from 0.4 to 3.0 dB with a median of 1.10 dB. To our knowledge, the present study is the first published article to describe adaptation of DPOAE in humans. These results should help advance the basic knowledge of human cochlear mechanics operating under the control of the MOC feedback system and contribute to the development of practical applications such as identifying people at high risk of acoustical injury and a clinical test of the functional status of the MOC system.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 08:36:58