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Titolo:
Three dimensional echocardiography documents haemodynamic improvement by biventricular pacing in patients with severe heart failure
Autore:
Kim, WY; Sogaard, P; Mortensen, PT; Jensen, HK; Pedersen, AK; Kristensen, BO; Egeblad, H;
Indirizzi:
Aarhus Univ Hosp, Dept Cardiol, Skejby Sygehus, DK-8000 Aarhus, Denmark Aarhus Univ Hosp Aarhus Denmark DK-8000 Sygehus, DK-8000 Aarhus, Denmark
Titolo Testata:
HEART
fascicolo: 5, volume: 85, anno: 2001,
pagine: 514 - 520
SICI:
1355-6037(200105)85:5<514:TDEDHI>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
DILATED CARDIOMYOPATHY; VOLUMETRIC FLOW; 3-DIMENSIONAL ECHOCARDIOGRAPHY; ATRIOVENTRICULAR DELAY; DOPPLER METHOD; COLOR DOPPLER; CHAMBER; QUANTIFICATION; VALIDATION; MECHANISM;
Keywords:
heart failure; left ventricular volume; pacing; three dimensional echocardiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, WY Aarhus Univ Hosp, Dept Cardiol, Skejby Sygehus, DK-8000 Aarhus, Denmark Aarhus Univ Hosp Aarhus Denmark DK-8000 DK-8000 Aarhus, Denmark
Citazione:
W.Y. Kim et al., "Three dimensional echocardiography documents haemodynamic improvement by biventricular pacing in patients with severe heart failure", HEART, 85(5), 2001, pp. 514-520

Abstract

Objectives--To quantify the short term haemodynamic effects of biventricular pacing in patients with heart failure and left bundle branch block by using three dimensional echocardiography. Design--Three dimensional echocardiography was performed in 15 consecutiveheart failure patients (New York Heart Association functional class III orIV) with an implanted biventricular pacing system. Six minute walk tests were performed to investigate the effect of biventricular pacing on exercisecapacity. Data were acquired at sinus rhythm and after short term (2-7 days) biventricular pacing. Results--Compared with baseline values, biventricular pacing significantlyreduced left ventricular end diastolic volume (EDV) by mean (SD) 4.0 (5.1)% (p < 0.01) and end systolic volume (ESV) by 5.6 (6.4)% (p < 0.02). Mitralregurgitant fraction was significantly reduced by 11 (12.1)% (p <less than> 0.003) and forward stroke volume (FSV) increased by 13.9 (18.6)% (p < 0.02). Exercise capacity was significantly improved with biventricular pacing by 48.4 (43.3)% (p < 0.00001). Regression analyses showed that the percentage increase in FSV independently predicted percentage improvement in walking distance (r(2) = 0.73, p < 0.0002). Both basal QRS duration and QRS narrowing predicted pacing efficacy, showing a significant correlation with %Delta EDV, %Delta ESV, and %Delta FSV. Conclusions--In five of 15 consecutive patients with heart failure and left bundle branch block, biventricular pacing induced a more than 15% increase in FSV, which predicted a more than 25% increase in walking distance and was accompanied by an immediate reduction in left ventricular chamber size and mitral regurgitation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 06:37:49