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Titolo:
Antibody libraries in drug and target discovery
Autore:
Rader, C;
Indirizzi:
Scripps Clin & Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA Scripps Clin & Res Inst La Jolla CA USA 92037 iol, La Jolla, CA 92037 USA
Titolo Testata:
DRUG DISCOVERY TODAY
fascicolo: 1, volume: 6, anno: 2001,
pagine: 36 - 43
SICI:
1359-6446(200101)6:1<36:ALIDAT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-AFFINITY ANTIBODIES; SINGLE-CHAIN FV; COMPLEMENTARITY-DETERMINING REGIONS; HUMAN MONOCLONAL-ANTIBODIES; PHAGE DISPLAY LIBRARIES; V-GENE LIBRARIES; T-CELL RECEPTOR; IN-VITRO; COMBINATORIAL LIBRARY; DIRECTED EVOLUTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
76
Recensione:
Indirizzi per estratti:
Indirizzo: Rader, C Scripps Clin & Res Inst, Dept Mol Biol, BCC-526,10550 N Torrey Pines Res, La Jolla, CA 92037 USA Scripps Clin & Res Inst BCC-526,10550 N Torrey Pines Res La Jolla CA USA 92037
Citazione:
C. Rader, "Antibody libraries in drug and target discovery", DRUG DISC T, 6(1), 2001, pp. 36-43

Abstract

Antibody libraries have come of age in the generation and evolution of monoclonal antibodies for therapeutic applications. Here, with an emphasis on cancer therapy, several examples are presented that illustrate the ability to design, engineer and select antibody libraries for different rationales in drug and target discovery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 10:06:15