Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The role of tumour necrosis factor-alpha in the pathogenes of complicated falciparum malaria
Autore:
Odeh, M;
Indirizzi:
Bnai Zion Med Ctr, Dept Internal Med, Haifa, Israel Bnai Zion Med Ctr Haifa Israel ed Ctr, Dept Internal Med, Haifa, Israel Technion Israel Inst Technol, Fac Med, Haifa, Israel Technion Israel Inst Technol Haifa Israel chnol, Fac Med, Haifa, Israel
Titolo Testata:
CYTOKINE
fascicolo: 1, volume: 14, anno: 2001,
pagine: 11 - 18
SICI:
1043-4666(20010407)14:1<11:TROTNF>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTERCELLULAR-ADHESION MOLECULE-1; RESPIRATORY-DISTRESS SYNDROME; HUMAN CEREBRAL MALARIA; NITRIC-OXIDE PRODUCTION; BRAIN-BARRIER DAMAGE; ACUTE LUNG INJURY; PLASMODIUM-FALCIPARUM; TNF-ALPHA; INTERFERON-GAMMA; AFRICAN CHILDREN;
Keywords:
TNF-alpha; complicated falciparum malaria;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
118
Recensione:
Indirizzi per estratti:
Indirizzo: Odeh, M POB 6477, IL-31063 Haifa, Israel POB 6477 Haifa Israel IL-31063POB 6477, IL-31063 Haifa, Israel
Citazione:
M. Odeh, "The role of tumour necrosis factor-alpha in the pathogenes of complicated falciparum malaria", CYTOKINE, 14(1), 2001, pp. 11-18

Abstract

Plasmodium falciparum malaria is the most important parasitic infection ofhumans and is one of the most serious health problems facing the inhabitants of developing countries. It is responsible for about 2 million deaths every year. To date there is no specific treatment for the disease apart fromanti-malarials, The declining sensitivity to these drugs is a serious therapeutic problem, while no safe and effective vaccine is likely to be available for general use in the near future. There is now abundant laboratory and clinical evidence to suggest that tumour necrosis factor-a (TNF-a) plays a major role in the pathogenesis of complicated falciparum malaria. Modulation of TNF-a response in combination with the current anti-malarial drugs, may represent a novel approach to the treatment of the serious complications associated with the disease. (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 20:33:40