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Titolo:
Trisomy 21 and isodicentric chromosome 21 in Kostmann syndrome following treatment with G-CSF
Autore:
Roland, B; Woodman, RC; Jorgenson, K; Pinto, A;
Indirizzi:
Univ Calgary, Dept Pathol & Lab Med, Calgary, AB T2N 1N4, Canada Univ Calgary Calgary AB Canada T2N 1N4 b Med, Calgary, AB T2N 1N4, Canada Univ Calgary, Dept Med, Calgary, AB T2N 1N4, Canada Univ Calgary Calgary AB Canada T2N 1N4 t Med, Calgary, AB T2N 1N4, Canada
Titolo Testata:
CANCER GENETICS AND CYTOGENETICS
fascicolo: 1, volume: 126, anno: 2001,
pagine: 78 - 80
SICI:
0165-4608(20010401)126:1<78:T2AIC2>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYELOID-LEUKEMIA; CONGENITAL AGRANULOCYTOSIS; TETRASOMY-21; NEUTROPENIA; MONOSOMY-7;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Roland, B Alberta Childrens Prov Gen Hosp, Dept Canc Cytogenet, 1820 Richmond Rd SW,Calgary, AB T2T 5C7, Canada Alberta Childrens Prov Gen Hosp 1820 Richmond Rd SW Calgary AB Canada T2T 5C7
Citazione:
B. Roland et al., "Trisomy 21 and isodicentric chromosome 21 in Kostmann syndrome following treatment with G-CSF", CANC GENET, 126(1), 2001, pp. 78-80

Abstract

A child with Kostmann syndrome, or severe congenital neutropenia, developed myelodysplastic syndrome after 6 years of treatment with rhG-CSF. The bone marrow karyotype showed acquired trisomy 21, and in some cells pentasomy 21 due to two isodicentric chromosomes 21. This is the second report of a patient with Kostmann syndrome and acquired trisomy 21. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 17:42:49