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Titolo:
The role of technetium-99m methoxyisobutyl isonitrile scintigraphy in suspected recurrent breast cancer
Autore:
Yildiz, A; Garipagaoglu, M; Gungor, F; Boz, A; Dalmaz, G;
Indirizzi:
Akdeniz Univ, Fac Med, Dept Nucl Med, TR-07070 Antalya, Turkey Akdeniz Univ Antalya Turkey TR-07070 Nucl Med, TR-07070 Antalya, Turkey Akdeniz Univ, Fac Med, Dept Radiat Oncol, TR-07070 Antalya, Turkey AkdenizUniv Antalya Turkey TR-07070 iat Oncol, TR-07070 Antalya, Turkey
Titolo Testata:
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
fascicolo: 2, volume: 16, anno: 2001,
pagine: 163 - 169
SICI:
1084-9785(200104)16:2<163:TROTMI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
TC-99M-MIBI SCINTIMAMMOGRAPHY; FOLLOW-UP; PLANAR; SPECT; LESIONS; MAMMOGRAPHY; DIAGNOSIS; CARCINOMA; MIBI;
Keywords:
recurrent breast cancer; technetium-99m methoxyisobutyl isonitrile; single-photon emission computed tomography; scintigraphy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Yildiz, A Akdeniz Univ, Fac Med, Dept Nucl Med, TR-07070 Antalya, Turkey Akdeniz Univ Antalya Turkey TR-07070 TR-07070 Antalya, Turkey
Citazione:
A. Yildiz et al., "The role of technetium-99m methoxyisobutyl isonitrile scintigraphy in suspected recurrent breast cancer", CANC BIO R, 16(2), 2001, pp. 163-169

Abstract

The aim of this study was to determine the role of technetium-99m methoxyisobutyl isonitrile (Tc-99m-MIBI) scintigraphy in the evaluation of recurrence and metastases in breast cancer patients with mastectomy and/or radiotherapy. A prospective study was designed to assess the accuracy of Tc-99m-MIBI scintigraphy in 36 patients (mean age 49 years) with suspected recurrent breast cancer. The scintigraphic studies were correlated with radiological findings and/or with histopathology. At 10-15 min after 740MBq Tc-99m-MIBI injection, standard planar images were obtained in prone lateral and anterior supine views and then single-photon emission computed tomography (SPECT)imaging was performed. A whole body imaging was also performed to demonstrate distant metastatic lesions. Totally 52 lesions were evaluated which 19 of them in 9 patients were malignant, while 33 lesions in 27 patients were benign. The sensitivity, was 33%, 88% and the specificity was 96%, 93% for planar and SPECT imaging, respectively in loco-regional lesions. Overall tile sensitivity and the specificity of MIBI imaging including whole bony were 89%, 81%, in other conventional radiological imaging methods were 95%, 65%, respectively. Tc-99m-MIBI scintigraphy using SPECT imaging may provide useful complementary information in patients with suspected recurrence breast cancer.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/06/19 alle ore 17:00:08