Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Lamotrigine: A review of clinical studies in bipolar disorders
Autore:
Zerjav-Lacombe, S; Tabarsi, E;
Indirizzi:
Riverview Hosp, Dept Pharm, Port Coquitlam, BC V3C 4J2, Canada Riverview Hosp Port Coquitlam BC Canada V3C 4J2 itlam, BC V3C 4J2, Canada Univ British Columbia, Fac Pharmaceut Sci, Vancouver, BC, Canada Univ British Columbia Vancouver BC Canada eut Sci, Vancouver, BC, Canada
Titolo Testata:
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
fascicolo: 4, volume: 46, anno: 2001,
pagine: 328 - 333
SICI:
0706-7437(200105)46:4<328:LAROCS>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
EFFICACY; MONOTHERAPY; DEPRESSION; VALPROATE; SPECTRUM; MANIA;
Keywords:
lamotrigine; bipolar disorder; nonresponders;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Zerjav-Lacombe, S Riverview Hosp, Dept Pharm, 500 Lougheed Highway, Port Coquitlam, BC V3C 4J2, Canada Riverview Hosp 500 Lougheed Highway Port Coquitlam BC Canada V3C 4J2
Citazione:
S. Zerjav-Lacombe e E. Tabarsi, "Lamotrigine: A review of clinical studies in bipolar disorders", CAN J PSY, 46(4), 2001, pp. 328-333

Abstract

Objective: This article reviews published studies on the use of lamotrigine in the treatment of bipolar disorder (BD). Method: We performed a Medline search to identify the literature data baseavailable on double-blind, open-label studies and case series on the use of lamotrigine to treat BD. Results: Three double-blind studies, 3 open-label studies, and 2 case series have been conducted to date (n = 401 patients). Most patients were either nonresponders or partial responders to other mood stabilizers. Overall, 50% to 83% of the patients responded to lamotrigine; doses in the studies ranged from 50 to 400 mg daily. Switching to mania while on 200 mg of lamotrigine or more was extremely rare, and there were no reports of serious adverse effects during the study periods. Conclusion: Lamotrigine is proving to be an effective agent in the treatment of BD and may be useful for patients who have not responded to other mood stabilizers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 04:05:18