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Titolo:
The efficacy of fluoxetine in improving physical symptoms associated with premenstrual dysphoric disorder
Autore:
Steiner, M; Romano, SJ; Babcock, S; Dillon, J; Shuler, C; Berger, C; Carter, D; Reid, R; Stewart, D; Steinberg, S; Judge, R;
Indirizzi:
McMaster Univ, St Josephs Hosp, Hamilton, ON L8N 4A6, Canada McMaster Univ Hamilton ON Canada L8N 4A6 sp, Hamilton, ON L8N 4A6, Canada Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & CoIndianapolis IN USA 46285 Labs, Indianapolis, IN 46285 USA St Marys Hosp, Montreal, PQ, Canada St Marys Hosp Montreal PQ CanadaSt Marys Hosp, Montreal, PQ, Canada British Columbia Womens Reprod Psychiat Program, Vancouver, BC, Canada British Columbia Womens Reprod Psychiat Program Vancouver BC Canada nada Queens Univ, Kingston, ON, Canada Queens Univ Kingston ON CanadaQueens Univ, Kingston, ON, Canada Univ Toronto, Univ Hlth Network, Toronto, ON, Canada Univ Toronto TorontoON Canada o, Univ Hlth Network, Toronto, ON, Canada
Titolo Testata:
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
fascicolo: 5, volume: 108, anno: 2001,
pagine: 462 - 468
SICI:
1470-0328(200105)108:5<462:TEOFII>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLACEBO-CONTROLLED TRIAL; ALLOPREGNANOLONE; CLOMIPRAMINE; SCALES; WOMEN; EPIDEMIOLOGY; RECEPTORS; SEROTONIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Steiner, M McMaster Univ, St Josephs Hosp, 50 Charlton Ave E, Hamilton, ONL8N 4A6, Canada McMaster Univ 50 Charlton Ave E Hamilton ON Canada L8N 4A6nada
Citazione:
M. Steiner et al., "The efficacy of fluoxetine in improving physical symptoms associated with premenstrual dysphoric disorder", BR J OBST G, 108(5), 2001, pp. 462-468

Abstract

Objective To determine the effectiveness of fluoxetine in alleviating physical symptoms of premenstrual dysphoric disorder. Design Randomised, double-blind, placebo controlled, parallel study. Setting Canadian University based outpatient clinics. Participants Four hundred and five subjects, of whom 320 with prospectively determined premenstrual dysphoric disorder were randomised. Methods Randomised women were assigned to fluoxetine 20 or 60 mg/day or placebo. Common physical symptoms associated with premenstrual dysphoric disorder including breast tenderness, bloating, and headache were evaluated by visual analog scales and the self-rated and observer premenstrual tension syndrome scales. Outcome measures Luteal phase change from mean baseline scores to mean treatment scores for all scales. Results Fluoxetine treatment was statistically superior to placebo, with no significant differences between the two fluoxetine dosages in their effects on physical symptoms. Conclusion Daily fluoxetine treatment is superior to placebo in improving the most common physical symptoms associated with premenstrual dysphoric disorder.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 08:07:00