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Titolo:
Prevalence and correlates of coronary calcification in black and white young adults - The coronary artery risk development in young adults - (CARDIA)study
Autore:
Bild, DE; Folsom, AR; Lowe, LP; Sidney, S; Kiefe, C; Westfall, AO; Zheng, ZJ; Rumberger, J;
Indirizzi:
NHLBI, DECA, NIH, Bethesda, MD 20892 USA NHLBI Bethesda MD USA 20892NHLBI, DECA, NIH, Bethesda, MD 20892 USA Univ Minnesota, Sch Publ Hlth, Dept Epidemiol, Minneapolis, MN USA Univ Minnesota Minneapolis MN USA h, Dept Epidemiol, Minneapolis, MN USA Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 Prevent Med, Chicago, IL 60611 USA Kaiser Permanente, Div Res, Oakland, CA USA Kaiser Permanente Oakland CA USA er Permanente, Div Res, Oakland, CA USA Univ Alabama, Dept Prevent Med, Birmingham, AL USA Univ Alabama Birmingham AL USA ama, Dept Prevent Med, Birmingham, AL USA Univ Alabama, Ctr Comprehens Canc, Birmingham, AL USA Univ Alabama Birmingham AL USA , Ctr Comprehens Canc, Birmingham, AL USA Ctr Dis Control, Atlanta, GA 30333 USA Ctr Dis Control Atlanta GA USA 30333 r Dis Control, Atlanta, GA 30333 USA Diagnost Cardiovasc Consultants, Columbus, OH USA Diagnost Cardiovasc Consultants Columbus OH USA ltants, Columbus, OH USA
Titolo Testata:
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
fascicolo: 5, volume: 21, anno: 2001,
pagine: 852 - 857
SICI:
1079-5642(200105)21:5<852:PACOCC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
BEAM COMPUTED-TOMOGRAPHY; DENSITY-LIPOPROTEIN CHOLESTEROL; HEART-DISEASE; CARDIOVASCULAR-DISEASE; BLOOD-PRESSURE; FOLLOW-UP; ATHEROSCLEROSIS; CALCIUM; ASSOCIATION; POPULATION;
Keywords:
coronary heart disease; risk factors; race; coronary artery calcification;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Bild, DE NHLBI, DECA, NIH, 2 Rockledge Ctr,6701 Rockledge Dr,MSC 7934, Bethesda, MD20892 USA NHLBI 2 Rockledge Ctr,6701 Rockledge Dr,MSC 7934 Bethesda MD USA 20892
Citazione:
D.E. Bild et al., "Prevalence and correlates of coronary calcification in black and white young adults - The coronary artery risk development in young adults - (CARDIA)study", ART THROM V, 21(5), 2001, pp. 852-857

Abstract

Whereas cardiovascular risk factor levels are substantially different in black and white Americans, the relative rates of cardiovascular disease in the 2 groups are not always consistent with these differences. To compare the prevalence of coronary calcification, an indicator of coronary atherosclerosis, in young adult blacks and whites, we performed electron-beam computed tomography of the heart in 443 men and women aged 28 to 40 years recruited from a population-based cohort. The presence of calcium. defined as at least 1 focus of at least 2.05 mm(2) in area and >130 Hounsfield units in density within the coronary arteries, was identified in 16.1% of black men, 11.8% of black women, 17.1% of white men, and 4.6% of white women (P=0.04 forcomparison across groups). Coronary calcium was associated with age and male sex, and after adjustment for age, race, and sex, coronary calcium was positively associated with body mass index, weight, systolic blood pressure.total cholesterol, low density lipoprotein cholesterol, triglycerides, andfasting insulin and negatively associated with education (all P<0.05). Independent risk factors included male sex, body mass index, and low density lipoprotein cholesterol. Race was not significantly associated with coronarycalcium in men or women, before or after adjustment for risk factors. Coronary calcification is associated with increased levels of cardiovascular risk factors in young adults, and its prevalence is not significantly different in blacks and whites.

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Documento generato il 03/12/20 alle ore 12:35:43