Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Simultaneous determination of nine water-soluble vitamins in pharmaceutical preparations by highperformance liquid chromatography with diode array detection
Autore:
Li, HB; Chen, F;
Indirizzi:
Univ Hong Kong, Dept Bot, Hong Kong, Hong Kong, Peoples R China Univ Hong Kong Hong Kong Hong Kong Peoples R China Kong, Peoples R China
Titolo Testata:
JOURNAL OF SEPARATION SCIENCE
fascicolo: 4, volume: 24, anno: 2001,
pagine: 271 - 274
SICI:
1615-9314(200104)24:4<271:SDONWV>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIVITAMIN TABLETS; HPLC; NICOTINAMIDE; RIBOFLAVIN; ACID;
Keywords:
vitamins; high performance liquid chromatography; drugs;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Chen, F Univ Hong Kong, Dept Bot, Pokfulam Rd, Hong Kong, Hong Kong, Peoples R China Univ Hong Kong Pokfulam Rd Hong Kong Hong Kong Peoples R China na
Citazione:
H.B. Li e F. Chen, "Simultaneous determination of nine water-soluble vitamins in pharmaceutical preparations by highperformance liquid chromatography with diode array detection", J SEP SCI, 24(4), 2001, pp. 271-274

Abstract

A simple and rapid method for the simultaneous determination of nine water-soluble vitamins was developed by high performance liquid chromatography with diode array detection. The water-soluble vitamins were analyzed by HPLCon a mu Bondapak C-18 column (300 x 3.9 mm, 10 mum) with methanol-0.1 mol/L KH2PO4 buffer (pH 7.0) as mobile phase (1.5 mL/min) in gradient mode as follows: in the range 0-7.0 min, 10:90; and in the range 8.0-15.0 min, 40:60(v/v). All nine water-soluble vitamins were separated in a single HPLC runwithin less than 15 min. The linearity of the calibration graphs was compound-dependent with correlation coefficients of 0.9986 to 0.9999 (n=6). The detection limits ranged from 0.02 mug/mL to 0.5 mug/mL. The method was successfully applied to the determination of vitamins in pharmaceutical preparations. The recoveries were from 95% to 102% and the relative standard deviations were in the range of 0.8% to 4.2%.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 09:02:20