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Titolo:
Nodular macroglossia with combined light chain and beta-2 microglobulin deposition in a long-term dialysis patient
Autore:
Bandini, S; Bergesio, F; Conti, P; Mancini, G; Cerretini, C; Cirami, C; Rosati, A; Caselli, GM; Arbustini, E; Merlini, G; Ficarra, G; Salvadori, M;
Indirizzi:
Univ Florence, Careggi Hosp, Dept Nephrol, Florence, Italy Univ Florence Florence Italy areggi Hosp, Dept Nephrol, Florence, Italy
Titolo Testata:
JOURNAL OF NEPHROLOGY
fascicolo: 2, volume: 14, anno: 2001,
pagine: 128 - 131
SICI:
1121-8428(200103/04)14:2<128:NMWCLC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYSTEMIC INVOLVEMENT; AMYLOIDOSIS; HEMODIALYSIS; TONGUE;
Keywords:
dialysis-related amyloidosis; macroglossia; beta-2-microglobulin; AL amyloidosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Bandini, S Univ Florence, Careggi Hosp, Dept Nephrol, Florence, Italy UnivFlorence Florence Italy , Dept Nephrol, Florence, Italy
Citazione:
S. Bandini et al., "Nodular macroglossia with combined light chain and beta-2 microglobulin deposition in a long-term dialysis patient", J NEPHROL, 14(2), 2001, pp. 128-131

Abstract

We describe a case in which nodular macroglossia, a very rare type of tongue involvement, tvas associated with the co-deposition of lambda light chain and beta-2 microglobulin fibrils in the tongue. The combined presence of two different amyloid fibrils did not lead to a more unfavourable clinical outcome. The believe that both these features often remain underdiagnosed and are in fact more frequent than reported. A careful clinical examination of the tongue together with serum immunofixation should be routine in all patients with dialysis-related amyloidosis in order to investigate the prevalence and type of tongue involvement and torule out other types of amyloidosis, In all cases of suspected mixed amyloidosis, immunohistochemical characterization of fibrils should be carried out by electron microscopy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 03:05:39