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Titolo:
Hemoglobin variants and determination of glycated hemoglobin (HbA(1C))
Autore:
Schnedl, WJ; Liebminger, A; Roller, RE; Lipp, RW; Krejs, GJ;
Indirizzi:
Karl Franzens Univ Graz, Dept Internal Med, Sch Med, A-8036 Graz, Austria Karl Franzens Univ Graz Graz Austria A-8036 ch Med, A-8036 Graz, Austria
Titolo Testata:
DIABETES-METABOLISM RESEARCH AND REVIEWS
fascicolo: 2, volume: 17, anno: 2001,
pagine: 94 - 98
SICI:
1520-7552(200103/04)17:2<94:HVADOG>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; CATION-EXCHANGE HPLC; DIABETES-MELLITUS; BETA-CHAIN; GLYCOSYLATED HEMOGLOBIN; ABNORMAL-HEMOGLOBINS; FALSELY LOW; C-TRAIT; HB; GLYCOHEMOGLOBIN;
Keywords:
hemoglobin variants; glycated hemoglobin; HbA(1C); determination methods;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
60
Recensione:
Indirizzi per estratti:
Indirizzo: Schnedl, WJ Karl Franzens Univ Graz, Dept Internal Med, Sch Med, Auenbruggerpl 15, A-8036 Graz, Austria Karl Franzens Univ Graz Auenbruggerpl 15 Graz Austria A-8036
Citazione:
W.J. Schnedl et al., "Hemoglobin variants and determination of glycated hemoglobin (HbA(1C))", DIABET M R, 17(2), 2001, pp. 94-98

Abstract

Measurement of glycated hemoglobin in diabetic patients is an established procedure for evaluating long-term control of diabetes. The Diabetes Control and Complications Trial (DCCT), as well as the United Kingdom ProspectiveDiabetes Study (UKPDS), confirmed the direct relationship between the degree of glycemic control as estimated by glycohemoglobin (GHb) determinationsand the development and progression of long-term complications in diabeticpatients. Samples with known interferences of HbA(1c) determination as hemoglobinopathies are specifically excluded from certification testing and there are no guidelines or requirements for comparability of samples containing hemoglobin (Hb) variants. This paper reviews the interference of Hb variants on determination methods of glycated hemoglobin as they result in false HbA(1c) results. Copyright (C) 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:52:54