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Titolo:
Hypercalcaemia in systemic lupus erythematosus
Autore:
Berar-Yanay, N; Weiner, P; Magadle, R;
Indirizzi:
Hillel Yaffe Med Ctr, Dept Med A, Hadera, Israel Hillel Yaffe Med Ctr Hadera Israel Med Ctr, Dept Med A, Hadera, Israel
Titolo Testata:
CLINICAL RHEUMATOLOGY
fascicolo: 2, volume: 20, anno: 2001,
pagine: 147 - 149
SICI:
0770-3198(2001)20:2<147:HISLE>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
HORMONE-RELATED PROTEIN; LYMPHEDEMA;
Keywords:
hypercalcaemia; SLE; PTHrP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Berar-Yanay, N Hillel Yaffe Med Ctr, Dept Med A, Hadera, Israel Hillel Yaffe Med Ctr Hadera Israel Med A, Hadera, Israel
Citazione:
N. Berar-Yanay et al., "Hypercalcaemia in systemic lupus erythematosus", CLIN RHEUMA, 20(2), 2001, pp. 147-149

Abstract

Hypercalcaemia is a common electrolyte abnormality. The vast majority of patients will be shown to have either hyperparathyroidism or malignancy. In less than 10% of patients other, less common causes of hypercalcaemia will be present. Systemic lupus erythematosus is a very rare cause of hypercalcaemia. It may be associated with lymphadenopathy and pleuritis to constitutea distinct clinical entity described as 'hypercalcaemia-lymphoedema syndrome'. Tn these cases the pathophysiology of the hypercalcaemia is not completely understood. In some cases it is associated with elevated levels of parathyroid-related peptide (PTHrP). In others the level of PTHrP is normal, and it has been suggested that autoantibodies may cause hypercalcaemia by activating the PTH receptor. We describe a case of a woman who presented withsevere hypercalcaemia, developed the hypercalcaemia-lymphodema syndrome and fulfilled the diagnostic criteria of systemic lupus erythematosus.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:26:42