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Titolo:
The discharge of a subset of serotonergic raphe magnus cells is influencedby baroreceptor input
Autore:
Gao, K; Mason, P;
Indirizzi:
Univ Chicago, Dept Neurobiol Pharmacol & Physiol, Chicago, IL 60637 USA Univ Chicago Chicago IL USA 60637 rmacol & Physiol, Chicago, IL 60637 USA
Titolo Testata:
BRAIN RESEARCH
fascicolo: 2, volume: 900, anno: 2001,
pagine: 306 - 313
SICI:
0006-8993(20010511)900:2<306:TDOASO>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYMPATHETIC PREGANGLIONIC NEURONS; THYROTROPIN-RELEASING-HORMONE; VENTROLATERAL MEDULLARY NEURONS; ROSTRAL VENTROMEDIAL MEDULLA; CAROTID-SINUS BARORECEPTORS; RAT BRAIN-STEM; SPINAL-CORD; CARDIOVASCULAR-RESPONSES; NERVOUS-SYSTEM; DORSAL HORN;
Keywords:
blood pressure; pain; autonomic modulation; heart rate; nociceptive modulation; monoamine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
62
Recensione:
Indirizzi per estratti:
Indirizzo: Mason, P Univ Chicago, Dept Neurobiol Pharmacol & Physiol, 947 E 58th St, Chicago, IL 60637 USA Univ Chicago 947 E 58th St Chicago IL USA 60637 ago, IL 60637 USA
Citazione:
K. Gao e P. Mason, "The discharge of a subset of serotonergic raphe magnus cells is influencedby baroreceptor input", BRAIN RES, 900(2), 2001, pp. 306-313

Abstract

In order to determine whether serotonergic cells in the medullary raphe magnus (RM) receive baroreceptor input, cells were tested for their responsesto descending aortic occlusion, aortic nerve stimulation, or systemic phenylephrine administration in the lightly anesthetized rat. Serotonergic cells were identified physiologically by a quantitative analysis of their slow and steady discharge. Greater than 40% of the serotonergic RM cells tested responded to brief occlusion of the descending aorta at the level of the coeliac arteries, a stimulus that elevated blood pressure by about 30 mmHg. Similarly, about 40% of the serotonergic RM cells responded to stimulation of the aortic nerve, a nerve that contains primarily baroreceptor afferents from the aortic arch. Greater than 70% of RM serotonergic cells responded to phenylephrine administration which elevated blood pressure by an average of 50 mmHg. Serotonergic cell responses to all methods of baroreceptor activation were small in magnitude and were largely restricted in time to the stimulus duration. The results indicate that a subset of serotonergic cells in RM are influenced by baroreceptor activity. (C) 2001 Published by Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 10:03:19