Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Gene and protein expression of brain-derived neurotrophic factor and TrkB in bone and cartilage
Autore:
Yamashiro, T; Fukunaga, T; Yamashita, K; Kobashi, N; Takano-Yamamoto, T;
Indirizzi:
Okayama Univ, Sch Dent, Dept Orthodont, Okayama 7008525, Japan Okayama Univ Okayama Japan 7008525 ept Orthodont, Okayama 7008525, Japan
Titolo Testata:
BONE
fascicolo: 4, volume: 28, anno: 2001,
pagine: 404 - 409
SICI:
8756-3282(200104)28:4<404:GAPEOB>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROWTH-FACTOR-I; MESSENGER-RNA; DIFFERENTIAL EXPRESSION; SUBSTANCE-P; RAT; RECEPTORS; SYSTEM; IMMUNOREACTIVITY; PATTERNS; PEPTIDE;
Keywords:
bone-derived neurotrophic factor (BDNF); TrkB; in situ hybridization; immunohistochemistry; osteoblast; chondrocyte;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Takano-Yamamoto, T Okayama Univ, Sch Dent, Dept Orthodont, 2-5-1 Shikata Cho, Okayama 7008525, Japan Okayama Univ 2-5-1 Shikata Cho Okayama Japan 7008525 n
Citazione:
T. Yamashiro et al., "Gene and protein expression of brain-derived neurotrophic factor and TrkB in bone and cartilage", BONE, 28(4), 2001, pp. 404-409

Abstract

Gene and protein expressions of brain-derived neurotrophic factor (BDNF) and TrkB, the high-affinity receptor of BDNF, were investigated in the femurand mandibular condyle of rats by in situ hybridization and immunohistochemistry. BDNF and TrkB mRNA showed overlapped expression in chondrocytes in proliferating and mature zones of the epiphyseal growth plate cartilage andmandibular condylar cartilage, and in cuboidal-shaped active osteoblasts at the site of endochondral and intramembranous ossification and in trabecular bone. Expression of BDNF protein also showed a similar localization. Thepresent study suggests that BDNF may participate in regulating the development and remodeling of bony tissue in the developing rat. (Bone 28:404-409;2001) (C) 2001 by Elsevier Science Inc, All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 15:35:29