Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Differences in energy metabolism and neuromuscular transmission between 30-Hz and 100-Hz stimulation in rat skeletal muscle
Autore:
Takata, S; Ikata, T;
Indirizzi:
Univ Tokushima, Sch Med, Dept Orthopaed Surg, Tokushima 770, Japan Univ Tokushima Tokushima Japan 770 Orthopaed Surg, Tokushima 770, Japan
Titolo Testata:
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
fascicolo: 5, volume: 82, anno: 2001,
pagine: 666 - 670
SICI:
0003-9993(200105)82:5<666:DIEMAN>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEAR MAGNETIC-RESONANCE; EXCITATION-FREQUENCY; FATIGUE; EXERCISE; CONTRACTIONS; RESPONSES; VOLUNTARY; RECOVERY;
Keywords:
electric stimulation; muscle contraction; rats, inbred WKY; rehabilitation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Takata, S 3-18-15 Kuramoto Cho, Tokushima 7708503, Japan 3-18-15 KuramotoCho Tokushima Japan 7708503 ma 7708503, Japan
Citazione:
S. Takata e T. Ikata, "Differences in energy metabolism and neuromuscular transmission between 30-Hz and 100-Hz stimulation in rat skeletal muscle", ARCH PHYS M, 82(5), 2001, pp. 666-670

Abstract

Objective: To examine differences in energy metabolism and neuromuscular transmission failure in rat hindlimb muscles subjected to electric stimulation at different frequencies. Design: Experimental animal study. Setting: Bioenergetic Research Center at Otsuka Pharmaceutical Company, Otsuka, Japan. Animals: Thirty-two 25-week-old male Wistar-Kyoto rats. Interventions: With the rat under general anesthesia, the sciatic nerve was electrically stimulated at 30Hz and 100Hz to induce muscle contraction. Main Outcome Measures: Energy level and intracellular pH of muscles by phosphorus-31 magnetic resonance spectroscopy (P-31-MRS); M-wave amplitude of muscles by electromyography. Results: During the first 4 minutes under stimulation at 30Hz and at 100Hz, energy level and intracellular pH dropped to their lowest values (p < .05or p < .01); the values then recovered with time. Recovery rates of energylevel and intracellular pH during stimulation at 100Hz were greater than those observed during stimulation at 30Hz. The M-wave amplitude during 100-Hz stimulation was permanently and significantly lower than that measured during 30-Hz stimulation(p < .01), and the recovery rate of M-wave amplitude after stimulation at 100Hz was slower than that after stimulation at 30Hz. Conclusion: Neuromuscular transmission failure was greater with 100-Hz stimulation than with 30-Hz stimulation. This finding may account for the rapid recovery of energy level and intracellular pH that occurs with stimulation at 100Hz.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:44:39