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Titolo:
QT intervals and QT dispersion as measures of left ventricular hypertrophyin an unselected hypertensive population
Autore:
Chapman, N; Mayet, J; Ozkor, M; Lampe, FC; Thom, SAM; Poulter, NR;
Indirizzi:
Imperial Coll Sch Med, Dept Clin Pharmacol, London W2 1NY, England Imperial Coll Sch Med London England W2 1NY acol, London W2 1NY, England Imperial Coll Sch Med, Dept Cardiol, London W2 1NY, England Imperial Coll Sch Med London England W2 1NY diol, London W2 1NY, England Royal Free & UCL Med Sch, Dept Primary Care & Populat Sci, London, EnglandRoyal Free & UCL Med Sch London England & Populat Sci, London, England Imperial Coll Sch Med, Pearl Rose Clin, London W2 1NY, England Imperial Coll Sch Med London England W2 1NY Clin, London W2 1NY, England
Titolo Testata:
AMERICAN JOURNAL OF HYPERTENSION
fascicolo: 5, volume: 14, anno: 2001,
parte:, 1
pagine: 455 - 462
SICI:
0895-7061(200105)14:5<455:QIAQDA>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; CHRONIC HEART-FAILURE; CARDIOVASCULAR MORTALITY; HEALTHY-SUBJECTS; ELECTROCARDIOGRAM; CARDIOMYOPATHY; ABNORMALITIES; ARRHYTHMIAS; VALIDATION; DEATH;
Keywords:
QT intervals; QT dispersion; ECG voltage criteria; left ventricular hypertrophy; hypertension;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Chapman, N Imperial Coll Sch Med, Dept Clin Pharmacol, St Marys,S Wharf Rd, London W21NY, England Imperial Coll Sch Med St Marys,S Wharf Rd London England W2 1NY
Citazione:
N. Chapman et al., "QT intervals and QT dispersion as measures of left ventricular hypertrophyin an unselected hypertensive population", AM J HYPERT, 14(5), 2001, pp. 455-462

Abstract

Electrocardiographic (ECG) QT intervals and dispersion correlate with echocardiographic left ventricular mass index (LVMI) in groups of selected essential hypertensives. We tested the strength of this relationship in a largegroup of unselected hypertensives to assess whether QT measurements may bea simple screening test for LVH in clinical practice. In a cross-sectionalstudy of 386 un selected hypertensive subjects, maximal QT intervals (QT(max)), QT dispersion (QT(disp)), and ECG voltages (Sokolow-Lyon and Cornell sex-specific voltages) were measured from 12-lead EGG. The LVMI correlated most strongly with Cornell voltage (linear regression r = 0.44, P < .001). The strongest relationship between LVMI and VT parameters was with QT(max),(r = 0,25, P < .001), This relationship weakened using heart rate-corrected QT(max). Correlations between LVMI and QT(disp) were weak, whether or notthey were corrected for heart rate. Sokolow-Lyon voltages, Cornell voltageand QT(max), but not QT(disp), were independently predictive of LVMI afteradjustment for age, sex, race, and the other ECG parameters. Receiver operating characteristic (ROC) curve analyses demonstrated that no QT parameterperformed better than simple ECG voltage criteria in the detection of LVH. In conclusion, QT(max), the QT parameter most strongly associated with LVMI, was independently associated with LVMI after adjustment for standard ECGvoltage criteria. However, as an isolated measure it was no better than simple ECG voltage criteria as a screening test for LVH in clinical practice. (C) 2001 American Journal of Hypertension, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:26:43