Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The effects of alcohol celiac plexus block, pain, and mood on longevity inpatients with unresectable pancreatic cancer: A double-blind, randomized, placebo-controlled study
Autore:
Staats, PS; Hekmat, H; Sauter, P; Lillemoe, K;
Indirizzi:
Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Div Pain Med, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 in Med, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 Oncol, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Dept Surg, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 t Surg, Baltimore, MD 21205 USA Univ Wisconsin, Dept Psychol, Stevens Point, WI 54481 USA Univ Wisconsin Stevens Point WI USA 54481 ol, Stevens Point, WI 54481 USA
Titolo Testata:
PAIN MEDICINE
fascicolo: 1, volume: 2, anno: 2001,
pagine: 28 - 34
SICI:
1526-2375(200103)2:1<28:TEOACP>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
SURVIVAL; MORPHINE; CARCINOMA;
Keywords:
pain; celiac plexus block; life expectancy; cancer; mood;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Staats, PS Johns Hopkins Univ, Sch Med, Dept Anesthesiol & Crit Care Med, Div Pain Med, 550 N Broadway,Suite 301, Baltimore, MD 21205 USA Johns Hopkins Univ 550 N Broadway,Suite 301 Baltimore MD USA 21205
Citazione:
P.S. Staats et al., "The effects of alcohol celiac plexus block, pain, and mood on longevity inpatients with unresectable pancreatic cancer: A double-blind, randomized, placebo-controlled study", PAIN MED, 2(1), 2001, pp. 28-34

Abstract

Objective. This additional analysis of data from a previously reported prospective trial comparing the effect of intraoperative alcohol or saline placebo neurolytic block in patients with pancreatic cancer was conducted in response to the development of a new theory, which explores the relationshipof negative mood states to pain, pain-related behavior, and ultimately, longevity. Methods. The original study used a double-blind procedure to randomly assign 139 patients with histologically proven, unresectable pancreatic cancer to receive either an alcohol or a saline block. Data on visual analog pain,mood, and interference with activity were collected preoperatively and every 2 months postoperatively until death. The current analysis was conductedon the complete data sets received from 130 patients. Demographic data were submitted to chi-square analysis and to univariate and multivariate analysis of variance. Univariate and multivariate analyses of variance also compared I) the effect of alcohol versus saline on pain, mood, interference of pain with activities, and longevity and 2) the impact of mood on pain with longevity as the dependent variable. Correlation and regression analyses examined the impact of mood on life expectancy. Results. The alcohol intervention had a significant positive effect on life duration and mood scores. High negative mood states correlated significantly with an increase in visual analog pain, the rating of pain intensity atits worse, and pain interference with patients' activities. Conclusion. In these subjects, the neurolytic block, as compared with medical management alone, improved pain, elevated mood, reduced pain interference with activity, and was associated with an increase in life expectancy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/02/20 alle ore 00:06:10