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Titolo:
Chemotherapy-evoked painful peripheral neuropathy
Autore:
Polomano, RC; Bennett, GJ;
Indirizzi:
Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Anesthesiol, Hershey, PA 17033 USA Penn State Univ Hershey PA USA 17033 t Anesthesiol, Hershey, PA 17033 USA Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Neurosci, Hershey, PA 17033 USA Penn State Univ Hershey PA USA 17033 Dept Neurosci, Hershey, PA 17033 USA Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Anat, Hershey, PA 17033 USA Penn State Univ Hershey PA USA 17033 ed, Dept Anat, Hershey, PA 17033 USA Med Coll Penn & Hahnemann Univ, Dept Neurol, Philadelphia, PA 19102 USA Med Coll Penn & Hahnemann Univ Philadelphia PA USA 19102 ia, PA 19102 USA
Titolo Testata:
PAIN MEDICINE
fascicolo: 1, volume: 2, anno: 2001,
pagine: 8 - 14
SICI:
1526-2375(200103)2:1<8:CPPN>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
TAXOL-INDUCED NEUROPATHY; SENSORY NEURONS; VINCRISTINE NEUROTOXICITY; REGENERATING AXONS; NERVE CRUSH; PACLITAXEL; RAT; CISPLATIN; AMELIORATION; MELANOMA;
Keywords:
allodynia; chemotherapy neurotoxicity; hyperalgesia; neuropathy; paclitaxel; painful neuropathy; vincristine;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Polomano, RC Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Anesthesiol, Hershey, PA 17033 USA Penn State Univ Hershey PA USA 17033 , Hershey, PA 17033 USA
Citazione:
R.C. Polomano e G.J. Bennett, "Chemotherapy-evoked painful peripheral neuropathy", PAIN MED, 2(1), 2001, pp. 8-14

Abstract

Vincristine and paclitaxel, two of the most effective drugs in the battle against cancer, produce a dose-limiting neurotoxicity that sometimes presents as a painful peripheral neuropathy. For the first time, investigators have been able to produce these chemotherapy-evoked painful peripheral neuropathies in the laboratory rat. These new models have already begun to elucidate the causes of the neuropathic pain associated with these antineoplasticdrugs, which will now make it possible to search for effective ways to prevent and treat it.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 05:30:08